| 产品: | AKR7A3 抗体 |
| 货号: | DF12819 |
| 描述: | Rabbit polyclonal antibody to AKR7A3 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 分子量: | 37 kDa; 37kD(Calculated). |
| 蛋白号: | O95154 |
| RRID: | AB_2845780 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12819, RRID:AB_2845780.
展开/折叠
AFAR 2; AFAR2; AFB1 aldehyde reductase 2; AFB1 AR 2; AFB1-AR 2; Aflatoxin aldehyde reductase; Aflatoxin B1 aldehyde reductase 2; Aflatoxin B1 aldehyde reductase member 3; Akr7a3; Aldo keto reductase family 7 member A3; ARK73_HUMAN; OTTHUMP00000002623;
抗原和靶标
- O95154 ARK73_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVTHECPNYFR
翻译修饰 - O95154 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S6 | Phosphorylation | Uniprot | |
| T12 | Phosphorylation | Uniprot | |
| R21 | Methylation | Uniprot | |
| T27 | Phosphorylation | Uniprot | |
| S28 | Phosphorylation | Uniprot | |
| T32 | Phosphorylation | Uniprot | |
| S85 | Phosphorylation | Uniprot | |
| S90 | Phosphorylation | Uniprot | |
| Y111 | Phosphorylation | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| S143 | Phosphorylation | Uniprot | |
| T227 | Phosphorylation | Uniprot | |
| S259 | Phosphorylation | Uniprot |
研究背景
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
Cytoplasm.
Expressed in colon, kidney, liver, pancreas, adenocarcinoma and endometrium.
Homodimer.
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
研究领域
· Metabolism > Xenobiotics biodegradation and metabolism > Metabolism of xenobiotics by cytochrome P450.
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