| 产品: | ALDH5A1 抗体 |
| 货号: | DF12820 |
| 描述: | Rabbit polyclonal antibody to ALDH5A1 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 51 kDa; 57kD(Calculated). |
| 蛋白号: | P51649 |
| RRID: | AB_2845781 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12820, RRID:AB_2845781.
展开/折叠
Aldedehyde dehydrogenase 5 family; Aldehyde dehydrogenase 5 family member A1; Aldehyde dehydrogenase 5A1; Aldehyde dehydrogenase family 5 member A1; ALDH5A 1; Aldh5a1; mitochondrial; Mitochondrial succinate semialdehyde dehydrogenase; NAD(+) dependent succinic semialdehyde dehydrogenase; NAD(+)-dependent succinic semialdehyde dehydrogenase; SSADH; SSDH; SSDH_HUMAN; Succinate semialdehyde dehydrogenase; Succinate-semialdehyde dehydrogenase;
抗原和靶标
- P51649 SSDH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGRLAGLSAALLRTDSFVGGRWLPAAATFPVQDPASGAALGMVADCGVREARAAVRAAYEAFCRWREVSAKERSSLLRKWYNLMIQNKDDLARIITAESGKPLKEAHGEILYSAFFLEWFSEEARRVYGDIIHTPAKDRRALVLKQPIGVAAVITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPFSALALAELASQAGIPSGVYNVIPCSRKNAKEVGEAICTDPLVSKISFTGSTTTGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNTGQTCVCSNQFLVQRGIHDAFVKAFAEAMKKNLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVSKGATVVTGGKRHQLGKNFFEPTLLCNVTQDMLCTHEETFGPLAPVIKFDTEEEAIAIANAADVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLELKYVCYGGL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P51649 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T3 | Phosphorylation | Uniprot | |
| S35 | Phosphorylation | Uniprot | |
| S55 | Phosphorylation | Uniprot | |
| T61 | Phosphorylation | Uniprot | |
| S63 | Phosphorylation | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| K126 | Acetylation | Uniprot | |
| Y128 | Phosphorylation | Uniprot | |
| K135 | Acetylation | Uniprot | |
| K148 | Ubiquitination | Uniprot | |
| Y175 | Phosphorylation | Uniprot | |
| T181 | Phosphorylation | P24941 (CDK2) | Uniprot |
| K214 | Acetylation | Uniprot | |
| K265 | Ubiquitination | Uniprot | |
| K279 | Ubiquitination | Uniprot | |
| T287 | Phosphorylation | Uniprot | |
| K301 | Ubiquitination | Uniprot | |
| K358 | Acetylation | Uniprot | |
| K365 | Acetylation | Uniprot | |
| T378 | Phosphorylation | Uniprot | |
| T379 | Phosphorylation | Uniprot | |
| K387 | Ubiquitination | Uniprot | |
| S498 | Phosphorylation | Uniprot | |
| S499 | Phosphorylation | Uniprot | |
| Y524 | Phosphorylation | Uniprot |
研究背景
Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
Mitochondrion.
Brain, pancreas, heart, liver, skeletal muscle and kidney. Lower in placenta.
Homotetramer.
Belongs to the aldehyde dehydrogenase family.
研究领域
· Metabolism > Amino acid metabolism > Alanine, aspartate and glutamate metabolism.
· Metabolism > Carbohydrate metabolism > Butanoate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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