产品: | BCAT2 抗体 |
货号: | DF12851 |
描述: | Rabbit polyclonal antibody to BCAT2 |
应用: | WB |
反应: | Human, Mouse, Rat |
预测: | Bovine |
分子量: | 42 kDa; 44kD(Calculated). |
蛋白号: | O15382 |
RRID: | AB_2845812 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12851, RRID:AB_2845812.
展开/折叠
BCAM; BCAT 2; BCAT(m); BCAT2; BCAT2_HUMAN; BCATM; BCT2; Branched chain aminotransferase 2, mitochondrial; Branched-chain-amino-acid aminotransferase; ECA40; mitochondrial; Placental protein 18; PP18;
抗原和靶标
- O15382 BCAT2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAAALGQIWARKLLSVPWLLCGPRRYASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O15382 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
K44 | Acetylation | Uniprot | |
K44 | Methylation | Uniprot | |
K73 | Acetylation | Uniprot | |
C135 | S-Nitrosylation | Uniprot | |
K141 | Acetylation | Uniprot | |
Y228 | Phosphorylation | Uniprot | |
K229 | Acetylation | Uniprot | |
K229 | Ubiquitination | Uniprot | |
K246 | Acetylation | Uniprot | |
K246 | Ubiquitination | Uniprot | |
K321 | Acetylation | Uniprot | |
K321 | Ubiquitination | Uniprot | |
C342 | S-Nitrosylation | Uniprot | |
C345 | S-Nitrosylation | Uniprot | |
K353 | Acetylation | Uniprot | |
K353 | Ubiquitination | Uniprot | |
K374 | Ubiquitination | Uniprot | |
K377 | Acetylation | Uniprot | |
K377 | Ubiquitination | Uniprot |
研究背景
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids.
Mitochondrion.
Cytoplasm.
Ubiquitous.
Homodimer.
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
研究领域
· Metabolism > Amino acid metabolism > Cysteine and methionine metabolism.
· Metabolism > Amino acid metabolism > Valine, leucine and isoleucine degradation.
· Metabolism > Amino acid metabolism > Valine, leucine and isoleucine biosynthesis.
· Metabolism > Metabolism of cofactors and vitamins > Pantothenate and CoA biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > 2-Oxocarboxylic acid metabolism.
· Metabolism > Global and overview maps > Biosynthesis of amino acids.
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