产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12863, RRID:AB_2845824.
展开/折叠
C14orf39; Chromosome 14 open reading frame 39; Protein SIX6OS1; S6OS1_HUMAN; Six6 opposite strand transcript 1; Six6os1;
抗原和靶标
- Q8N1H7 S6OS1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNDSLFVSLDRLLLEFVFQYEQDISTKEEMIQRINKCCEDIKENKVTICRIHETINATDEEIDHYCKHSEEIKDNCRNWKPTCDVFRKHEDYMQDQFTVYQGTVEKDKEMYHDYICQYKEVLKQYQLKYSETPFSREYYEKKREHEEIQSRVLACTEQLKMNETIFMKFRVPAPFPSLTKWTLNIVNLRCETQDILKHASNLTKSSSELKKEVDEMEIEINYLNQQISRHNETKALSETLEEKNKNTENRKELKERIFGKDEHVLTLNKTQSSQLFLPYESQKLVRPIKMHSSEPRVADIKEESSAKQSKLANIDFRQKENDTQIFNDSAVDNHSKCSHITTITSSQKFMQVRLLTPQKQSNSNQWSEKGDKDAEYGDKGTVRQVRESKCTSQAIYTEHFGKSVENDSDEVEERAENFPRTSEIPIFLGTPKAVKAPESLEKIKFPKTPPFEINRNRNAVPEVQTEKESPGLSFLMSYTSRSPGLNLFDSSVFDTEISSDQFNEHYSARNLNPLSSEQEIGNLLEKPEGEDGFTFSFPSDTSTHTFGAGKDDFSFPFSFGQGQNSIPSSSLKGFSSSSQNTTQFTFF
翻译修饰 - Q8N1H7 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K80 | Ubiquitination | Uniprot | |
| Y129 | Phosphorylation | Uniprot | |
| Y139 | Phosphorylation | Uniprot | |
| T247 | Phosphorylation | Uniprot | |
| K283 | Acetylation | Uniprot | |
| T465 | Phosphorylation | Uniprot |
研究背景
Meiotic protein that localizes to the central element of the synaptonemal complex and is required for chromosome synapsis during meiotic recombination. Required for the appropriate processing of intermediate recombination nodules before crossover formation.
Chromosome.
Note: Component of the central element of the synaptonemal complex. In spermatocytes, detected from zygonema to pachynema and localizes along synapsed lateral elements. Loading to the central element of the synaptonemal complex is dependent on the assembly of the tripartite synaptonemal complex structure that occurs upon synapsis between homologous chromosomes.
Highest expression in retina, skeletal muscle and colon.
Interacts with SYCE1. Interacts with proteasome subunit PSMA8; to participate in meiosis progression during spermatogenesis (By similarity).
限制条款
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