产品: C17orf28 抗体
货号: DF12865
描述: Rabbit polyclonal antibody to C17orf28
应用: WB
反应: Human, Mouse, Rat
预测: Pig, Bovine, Horse, Sheep, Dog, Chicken
分子量: 89 kDa; 89kD(Calculated).
蛋白号: Q8IV36
RRID: AB_2845826

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Dog(100%), Chicken(100%)
克隆:
Polyclonal
特异性:
C17orf28 Antibody detects endogenous levels of total C17orf28.
RRID:
AB_2845826
引用格式: Affinity Biosciences Cat# DF12865, RRID:AB_2845826.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

C17orf28; Chromosome 17 open reading frame 28; CQ028_HUMAN; DMC1; Down regulated in multiple cancers 1; Down-regulated in multiple cancers 1; Downregulated in multiple cancer 1; FLJ43526; HID 1; HID1; HID1 domain containing; HID1 domain containing protein; Hypothetical protein LOC283987; Protein hid 1 homolog; Protein HID1; UPF0663 transmembrane protein C17orf28;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q8IV36 HID1_HUMAN:

Expressed in heart, skeletal muscle, colon, spleen, kidney, liver, small intestine and lung. Highest expression is seen in brain and placenta. Loss of expression is seen in some breast, cervical, hepatocellular, lung, thyroid, gastric and renal cell-cancer lines. Highly expressed in secretory cell lines.

序列:
MGSTDSKLNFRKAVIQLTTKTQPVEATDDAFWDQFWADTATSVQDVFALVPAAEIRAVREESPSNLATLCYKAVEKLVQGAESGCHSEKEKQIVLNCSRLLTRVLPYIFEDPDWRGFFWSTVPGAGRGGQGEEDDEHARPLAESLLLAIADLLFCPDFTVQSHRRSTVDSAEDVHSLDSCEYIWEAGVGFAHSPQPNYIHDMNRMELLKLLLTCFSEAMYLPPAPESGSTNPWVQFFCSTENRHALPLFTSLLNTVCAYDPVGYGIPYNHLLFSDYREPLVEEAAQVLIVTLDHDSASSASPTVDGTTTGTAMDDADPPGPENLFVNYLSRIHREEDFQFILKGIARLLSNPLLQTYLPNSTKKIQFHQELLVLFWKLCDFNKKFLFFVLKSSDVLDILVPILFFLNDARADQSRVGLMHIGVFILLLLSGERNFGVRLNKPYSIRVPMDIPVFTGTHADLLIVVFHKIITSGHQRLQPLFDCLLTIVVNVSPYLKSLSMVTANKLLHLLEAFSTTWFLFSAAQNHHLVFFLLEVFNNIIQYQFDGNSNLVYAIIRKRSIFHQLANLPTDPPTIHKALQRRRRTPEPLSRTGSQEGTSMEGSRPAAPAEPGTLKTSLVATPGIDKLTEKSQVSEDGTLRSLEPEPQQSLEDGSPAKGEPSQAWREQRRPSTSSASGQWSPTPEWVLSWKSKLPLQTIMRLLQVLVPQVEKICIDKGLTDESEILRFLQHGTLVGLLPVPHPILIRKYQANSGTAMWFRTYMWGVIYLRNVDPPVWYDTDVKLFEIQRV

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Xenopus
75
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q8IV36 作为底物

Site PTM Type Enzyme
G2 Myristoylation
T4 Phosphorylation
S6 Phosphorylation
T121 Phosphorylation
S144 Phosphorylation
S170 Phosphorylation
K363 Ubiquitination
S430 Phosphorylation
S559 Phosphorylation
T584 Phosphorylation
S589 Phosphorylation
T591 Phosphorylation
S593 Phosphorylation
T597 Phosphorylation
S616 Phosphorylation
T620 Phosphorylation
S640 Phosphorylation
S648 Phosphorylation
S653 Phosphorylation
S670 Phosphorylation
T671 Phosphorylation
S672 Phosphorylation
S673 Phosphorylation
S675 Phosphorylation
S679 Phosphorylation
T681 Phosphorylation
Y747 Phosphorylation

研究背景

功能:

May play an important role in the development of cancers in a broad range of tissues.

细胞定位:

Cytoplasm. Golgi apparatus membrane>Lipid-anchor.
Note: Shuttles between the cytosol and the Golgi apparatus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in heart, skeletal muscle, colon, spleen, kidney, liver, small intestine and lung. Highest expression is seen in brain and placenta. Loss of expression is seen in some breast, cervical, hepatocellular, lung, thyroid, gastric and renal cell-cancer lines. Highly expressed in secretory cell lines.

蛋白家族:

Belongs to the hid-1 family.

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