| 产品: | COQ5 抗体 |
| 货号: | DF12910 |
| 描述: | Rabbit polyclonal antibody to COQ5 |
| 应用: | WB |
| 反应: | Human, Mouse |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 37 kDa, 30 kDa; 37kD(Calculated). |
| 蛋白号: | Q5HYK3 |
| RRID: | AB_2845871 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12910, RRID:AB_2845871.
展开/折叠
2-methoxy-6-polyprenyl-1; 4-benzoquinol methylase; COQ5; COQ5_HUMAN; mitochondrial; Ubiquinone biosynthesis methyltransferase COQ5; Ubiquinone biosynthesis methyltransferase COQ5, mitochondrial;
抗原和靶标
Widely expressed, with highest levels in liver, lung, placenta and skeletal muscle.
- Q5HYK3 COQ5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAPGSCALWSYCGRGWSRAMRGCQLLGLRSSWPGDLLSARLLSQEKRAAETHFGFETVSEEEKGGKVYQVFESVAKKYDVMNDMMSLGIHRVWKDLLLWKMHPLPGTQLLDVAGGTGDIAFRFLNYVQSQHQRKQKRQLRAQQNLSWEEIAKEYQNEEDSLGGSRVVVCDINKEMLKVGKQKALAQGYRAGLAWVLGDAEELPFDDDKFDIYTIAFGIRNVTHIDQALQEAHRVLKPGGRFLCLEFSQVNNPLISRLYDLYSFQVIPVLGEVIAGDWKSYQYLVESIRRFPSQEEFKDMIEDAGFHKVTYESLTSGIVAIHSGFKL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q5HYK3 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T58 | Phosphorylation | Uniprot | |
| S60 | Phosphorylation | Uniprot | |
| Y69 | Phosphorylation | Uniprot | |
| K95 | Ubiquitination | Uniprot | |
| Y283 | Phosphorylation | Uniprot |
研究背景
Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
Mitochondrion inner membrane>Peripheral membrane protein>Matrix side.
Widely expressed, with highest levels in liver, lung, placenta and skeletal muscle.
Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
研究领域
· Metabolism > Metabolism of cofactors and vitamins > Ubiquinone and other terpenoid-quinone biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
限制条款
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