| 产品: | DHX15 抗体 |
| 货号: | DF12939 |
| 描述: | Rabbit polyclonal antibody to DHX15 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 91 kDa; 91kD(Calculated). |
| 蛋白号: | O43143 |
| RRID: | AB_2845900 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12939, RRID:AB_2845900.
展开/折叠
ATP dependent RNA helicase #46; ATP-dependent RNA helicase #46; DBP1; DDX15; DEADH box 15; DEAH (Asp Glu Ala His) box polypeptide 15; DEAH box polypeptide 15; DEAH box protein 15; DHX15; DHX15_HUMAN; HRH2; Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; PRP43; PrPp43p; RNA helicase 2;
抗原和靶标
- O43143 DHX15_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSKRHRLDLGEDYPSGKKRAGTDGKDRDRDRDREDRSKDRDRERDRGDREREREKEKEKELRASTNAMLISAGLPPLKASHSAHSTHSAHSTHSTHSAHSTHAGHAGHTSLPQCINPFTNLPHTPRYYDILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHPSTVLDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSNFPQCEAKRQLDRIIAKLQSKEYSQY
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O43143 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K3 | Acetylation | Uniprot | |
| Y13 | Phosphorylation | Uniprot | |
| S15 | Phosphorylation | Uniprot | |
| K17 | Acetylation | Uniprot | |
| K17 | Ubiquitination | Uniprot | |
| K18 | Acetylation | Uniprot | |
| K18 | Methylation | Uniprot | |
| R42 | Methylation | Uniprot | |
| R44 | Methylation | Uniprot | |
| S71 | Phosphorylation | Uniprot | |
| Y128 | Phosphorylation | Uniprot | |
| K132 | Acetylation | Uniprot | |
| K132 | Ubiquitination | Uniprot | |
| Y142 | Phosphorylation | Uniprot | |
| K143 | Ubiquitination | Uniprot | |
| S155 | Phosphorylation | Uniprot | |
| T162 | Phosphorylation | Uniprot | |
| S164 | Phosphorylation | Uniprot | |
| K166 | Acetylation | Uniprot | |
| K185 | Acetylation | Uniprot | |
| C190 | S-Nitrosylation | Uniprot | |
| K230 | Ubiquitination | Uniprot | |
| K234 | Ubiquitination | Uniprot | |
| Y254 | Phosphorylation | Uniprot | |
| T266 | Phosphorylation | Uniprot | |
| S292 | Phosphorylation | Uniprot | |
| T324 | Phosphorylation | Uniprot | |
| Y331 | Phosphorylation | Uniprot | |
| K370 | Ubiquitination | Uniprot | |
| K384 | Ubiquitination | Uniprot | |
| K407 | Ubiquitination | Uniprot | |
| K445 | Acetylation | Uniprot | |
| K445 | Ubiquitination | Uniprot | |
| K463 | Ubiquitination | Uniprot | |
| T476 | Phosphorylation | Uniprot | |
| K480 | Ubiquitination | Uniprot | |
| K488 | Acetylation | Uniprot | |
| K488 | Ubiquitination | Uniprot | |
| Y490 | Phosphorylation | Uniprot | |
| K491 | Sumoylation | Uniprot | |
| K491 | Ubiquitination | Uniprot | |
| Y499 | Phosphorylation | Uniprot | |
| S505 | Phosphorylation | Uniprot | |
| S509 | Phosphorylation | Uniprot | |
| K515 | Ubiquitination | Uniprot | |
| K516 | Ubiquitination | Uniprot | |
| K614 | Ubiquitination | Uniprot | |
| Y631 | Phosphorylation | Uniprot | |
| S653 | Phosphorylation | Uniprot | |
| R670 | Methylation | Uniprot | |
| Y686 | Phosphorylation | Uniprot | |
| T695 | Phosphorylation | Uniprot | |
| Y710 | Phosphorylation | Uniprot | |
| K754 | Acetylation | Uniprot | |
| K754 | Ubiquitination | Uniprot | |
| K760 | Ubiquitination | Uniprot | |
| K777 | Ubiquitination | Uniprot | |
| K786 | Acetylation | Uniprot | |
| K786 | Ubiquitination | Uniprot | |
| K790 | Ubiquitination | Uniprot | |
| Y792 | Phosphorylation | Uniprot | |
| S793 | Phosphorylation | Uniprot | |
| Y795 | Phosphorylation | Uniprot |
研究背景
Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns.
Nucleus. Nucleus>Nucleolus.
Ubiquitous.
Interacts with SSB/La. Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Identified in the Intron Large (IL) complex, a post-mRNA release spliceosomal complex containing the excised intron, U2, U5 and U6 snRNPs, and splicing factors; the association may be transient. Interacts with TFIP11; indicative for a recruitment to the IL complex. Interacts with GPATCH2.
Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.
研究领域
· Genetic Information Processing > Transcription > Spliceosome.
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