| 产品: | DYNLL2 抗体 |
| 货号: | DF12966 |
| 描述: | Rabbit polyclonal antibody to DYNLL2 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 10 kDa; 10kD(Calculated). |
| 蛋白号: | Q96FJ2 |
| RRID: | AB_2845927 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF12966, RRID:AB_2845927.
展开/折叠
8 kDa dynein light chain b; C87222; cytoplasmic; Dlc2; DLC8b; DNCL1B; DYL2_HUMAN; Dynein light chain 2; Dynein light chain 2, cytoplasmic; Dynein light chain LC8 type 2; Dynein light chain LC8-type 2; Dynll2; MGC17810; MGC72334;
抗原和靶标
- Q96FJ2 DYL2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSDRKAVIKNADMSEDMQQDAVDCATQAMEKYNIEKDIAAYIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q96FJ2 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K5 | Acetylation | Uniprot | |
| S14 | Phosphorylation | Uniprot | |
| K31 | Ubiquitination | Uniprot | |
| Y32 | Phosphorylation | Uniprot | |
| K36 | Acetylation | Uniprot | |
| K36 | Ubiquitination | Uniprot | |
| Y41 | Phosphorylation | Uniprot | |
| K49 | Methylation | Uniprot | |
| K49 | Sumoylation | Uniprot | |
| K49 | Ubiquitination | Uniprot | |
| S64 | Phosphorylation | Uniprot | |
| Y65 | Phosphorylation | Uniprot | |
| T67 | Phosphorylation | Uniprot | |
| S88 | Phosphorylation | Uniprot |
研究背景
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity).
Cytoplasm>Cytoskeleton.
Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. Dynein ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer. Interacts with DYNC1I1. Interacts with BMF. Component of the myosin V motor complex. Interacts with BCAS1. Interacts with Basson/BSN.
Belongs to the dynein light chain family.
研究领域
· Organismal Systems > Excretory system > Vasopressin-regulated water reabsorption.
限制条款
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