产品: KLF13 抗体
货号: DF13113
描述: Rabbit polyclonal antibody to KLF13
应用: WB IHC
反应: Human, Rat
预测: Pig, Zebrafish, Bovine, Xenopus
分子量: 45 kDa; 31kD(Calculated).
蛋白号: Q9Y2Y9
RRID: AB_2846073

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Rat
预测:
Pig(92%), Zebrafish(92%), Bovine(100%), Xenopus(100%)
克隆:
Polyclonal
特异性:
KLF13 Antibody detects endogenous levels of total KLF13.
RRID:
AB_2846073
引用格式: Affinity Biosciences Cat# DF13113, RRID:AB_2846073.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Basic transcription element binding protein 3; Basic transcription element-binding protein 3; BTE binding protein 3; BTE-binding protein 3; BTEB3; C2 H2 zinc finger protein; FKLF 2; FKLF2; Klf13; KLF13_HUMAN; Krueppel-like factor 13; Kruppel like factor 13; Novel Sp1 like zinc finger transcription factor; Novel Sp1-like zinc finger transcription factor 1; NSLP1; RANTES factor of late activated T lymphocytes 1; RANTES factor of late activated T-lymphocytes 1; RFLAT 1; RFLAT-1; RFLAT1; Transcription factor BTEB3; Transcription factor NSLP1;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q9Y2Y9 KLF13_HUMAN:

Ubiquitous.

序列:
MAAAAYVDHFAAECLVSMSSRAVVHGPREGPESRPEGAAVAATPTLPRVEERRDGKDSASLFVVARILADLNQQAPAPAPAERREGAAARKARTPCRLPPPAPEPTSPGAEGAAAAPPSPAWSEPEPEAGLEPEREPGPAGSGEPGLRQRVRRGRSRADLESPQRKHKCHYAGCEKVYGKSSHLKAHLRTHTGERPFACSWQDCNKKFARSDELARHYRTHTGEKKFSCPICEKRFMRSDHLTKHARRHANFHPGMLQRRGGGSRTGSLSDYSRSDASSPTISPASSP

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Bovine
100
Xenopus
100
Pig
92
Zebrafish
92
Horse
0
Sheep
0
Dog
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9Y2Y9 作为底物

Site PTM Type Enzyme
T43 Phosphorylation
K56 Ubiquitination
S60 Phosphorylation
S119 Phosphorylation
S123 Phosphorylation
S162 Phosphorylation
K166 Acetylation
K168 Acetylation
K168 Ubiquitination
K176 Ubiquitination
K180 Acetylation
K180 Ubiquitination
K185 Sumoylation
K185 Ubiquitination
T192 Phosphorylation
K206 Ubiquitination
T220 Phosphorylation
T222 Phosphorylation
K225 Acetylation
K225 Ubiquitination
K226 Acetylation
K226 Ubiquitination
K234 Ubiquitination
K244 Ubiquitination
S268 Phosphorylation
S270 Phosphorylation
S279 Phosphorylation
T281 Phosphorylation
S283 Phosphorylation
S287 Phosphorylation

研究背景

功能:

Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.

翻译修饰:

Phosphorylated.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitous.

蛋白家族:

The Ala/Pro-rich domain may contain discrete activation and repression subdomains and also can mediate protein-protein interactions.

Belongs to the Sp1 C2H2-type zinc-finger protein family.

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