产品: | KLF13 抗体 |
货号: | DF13113 |
描述: | Rabbit polyclonal antibody to KLF13 |
应用: | WB IHC |
反应: | Human, Rat |
预测: | Pig, Zebrafish, Bovine, Xenopus |
分子量: | 45 kDa; 31kD(Calculated). |
蛋白号: | Q9Y2Y9 |
RRID: | AB_2846073 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF13113, RRID:AB_2846073.
展开/折叠
Basic transcription element binding protein 3; Basic transcription element-binding protein 3; BTE binding protein 3; BTE-binding protein 3; BTEB3; C2 H2 zinc finger protein; FKLF 2; FKLF2; Klf13; KLF13_HUMAN; Krueppel-like factor 13; Kruppel like factor 13; Novel Sp1 like zinc finger transcription factor; Novel Sp1-like zinc finger transcription factor 1; NSLP1; RANTES factor of late activated T lymphocytes 1; RANTES factor of late activated T-lymphocytes 1; RFLAT 1; RFLAT-1; RFLAT1; Transcription factor BTEB3; Transcription factor NSLP1;
抗原和靶标
- Q9Y2Y9 KLF13_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAAAYVDHFAAECLVSMSSRAVVHGPREGPESRPEGAAVAATPTLPRVEERRDGKDSASLFVVARILADLNQQAPAPAPAERREGAAARKARTPCRLPPPAPEPTSPGAEGAAAAPPSPAWSEPEPEAGLEPEREPGPAGSGEPGLRQRVRRGRSRADLESPQRKHKCHYAGCEKVYGKSSHLKAHLRTHTGERPFACSWQDCNKKFARSDELARHYRTHTGEKKFSCPICEKRFMRSDHLTKHARRHANFHPGMLQRRGGGSRTGSLSDYSRSDASSPTISPASSP
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q9Y2Y9 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T43 | Phosphorylation | Uniprot | |
K56 | Ubiquitination | Uniprot | |
S60 | Phosphorylation | Uniprot | |
S119 | Phosphorylation | Uniprot | |
S123 | Phosphorylation | Uniprot | |
S162 | Phosphorylation | Uniprot | |
K166 | Acetylation | Uniprot | |
K168 | Acetylation | Uniprot | |
K168 | Ubiquitination | Uniprot | |
K176 | Ubiquitination | Uniprot | |
K180 | Acetylation | Uniprot | |
K180 | Ubiquitination | Uniprot | |
K185 | Sumoylation | Uniprot | |
K185 | Ubiquitination | Uniprot | |
T192 | Phosphorylation | Uniprot | |
K206 | Ubiquitination | Uniprot | |
T220 | Phosphorylation | Uniprot | |
T222 | Phosphorylation | Uniprot | |
K225 | Acetylation | Uniprot | |
K225 | Ubiquitination | Uniprot | |
K226 | Acetylation | Uniprot | |
K226 | Ubiquitination | Uniprot | |
K234 | Ubiquitination | Uniprot | |
K244 | Ubiquitination | Uniprot | |
S268 | Phosphorylation | Uniprot | |
S270 | Phosphorylation | Uniprot | |
S279 | Phosphorylation | Uniprot | |
T281 | Phosphorylation | Uniprot | |
S283 | Phosphorylation | Uniprot | |
S287 | Phosphorylation | Uniprot |
研究背景
Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.
Phosphorylated.
Nucleus.
Ubiquitous.
The Ala/Pro-rich domain may contain discrete activation and repression subdomains and also can mediate protein-protein interactions.
Belongs to the Sp1 C2H2-type zinc-finger protein family.
限制条款
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