| 产品: | MTA2 抗体 |
| 货号: | DF13292 |
| 描述: | Rabbit polyclonal antibody to MTA2 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 75kDa; 75kD(Calculated). |
| 蛋白号: | O94776 |
| RRID: | AB_2846311 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF13292, RRID:AB_2846311.
展开/折叠
DKFZp686F2281; Mata1l1; Metastasis associated 1 family member 2; Metastasis associated 1 like 1; Metastasis associated gene 1 like 1; Metastasis associated gene family member 2; Metastasis associated protein 2; Metastasis associated protein MTA 2; Metastasis associated protein MTA2; Mmta2; MTA1 L1 protein; MTA1L1; p53 target protein in deacetylase complex; PID;
抗原和靶标
- O94776 MTA2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAANMYRVGDYVYFENSSSNPYLVRRIEELNKTANGNVEAKVVCLFRRRDISSSLNSLADSNAREFEEESKQPGVSEQQRHQLKHRELFLSRQFESLPATHIRGKCSVTLLNETDILSQYLEKEDCFFYSLVFDPVQKTLLADQGEIRVGCKYQAEIPDRLVEGESDNRNQQKMEMKVWDPDNPLTDRQIDQFLVVARAVGTFARALDCSSSIRQPSLHMSAAAASRDITLFHAMDTLQRNGYDLAKAMSTLVPQGGPVLCRDEMEEWSASEAMLFEEALEKYGKDFNDIRQDFLPWKSLASIVQFYYMWKTTDRYIQQKRLKAAEADSKLKQVYIPTYTKPNPNQIISVGSKPGMNGAGFQKGLTCESCHTTQSAQWYAWGPPNMQCRLCASCWIYWKKYGGLKTPTQLEGATRGTTEPHSRGHLSRPEAQSLSPYTTSANRAKLLAKNRQTFLLQTTKLTRLARRMCRDLLQPRRAARRPYAPINANAIKAECSIRLPKAAKTPLKIHPLVRLPLATIVKDLVAQAPLKPKTPRGTKTPINRNQLSQNRGLGGIMVKRAYETMAGAGVPFSANGRPLASGIRSSSQPAAKRQKLNPADAPNPVVFVATKDTRALRKALTHLEMRRAARRPNLPLKVKPTLIAVRPPVPLPAPSHPASTNEPIVLED
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O94776 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y11 | Phosphorylation | Uniprot | |
| Y13 | Phosphorylation | Uniprot | |
| Y22 | Phosphorylation | Uniprot | |
| K32 | Ubiquitination | Uniprot | |
| K41 | Ubiquitination | Uniprot | |
| S52 | Phosphorylation | Uniprot | |
| S54 | Phosphorylation | Uniprot | |
| S57 | Phosphorylation | Uniprot | |
| S61 | Phosphorylation | Uniprot | |
| K71 | Ubiquitination | Uniprot | |
| K152 | Acetylation | Uniprot | |
| K152 | Ubiquitination | Uniprot | |
| R160 | Methylation | Uniprot | |
| R169 | Methylation | Uniprot | |
| K173 | Methylation | Uniprot | |
| K173 | Ubiquitination | Uniprot | |
| K177 | Ubiquitination | Uniprot | |
| R188 | Methylation | Uniprot | |
| S221 | Phosphorylation | Uniprot | |
| K282 | Ubiquitination | Uniprot | |
| K285 | Ubiquitination | Uniprot | |
| K320 | Ubiquitination | Uniprot | |
| K332 | Acetylation | Uniprot | |
| Y335 | Phosphorylation | Uniprot | |
| Y339 | Phosphorylation | Uniprot | |
| K341 | Acetylation | Uniprot | |
| K341 | Ubiquitination | Uniprot | |
| S352 | Phosphorylation | Uniprot | |
| S393 | Phosphorylation | Uniprot | |
| Y397 | Phosphorylation | Uniprot | |
| K405 | Ubiquitination | Uniprot | |
| T406 | Phosphorylation | Uniprot | |
| S427 | Phosphorylation | Uniprot | |
| S433 | Phosphorylation | Uniprot | |
| S435 | Phosphorylation | P24941 (CDK2) | Uniprot |
| Y437 | Phosphorylation | Uniprot | |
| T438 | Phosphorylation | P24941 (CDK2) | Uniprot |
| T439 | Phosphorylation | P24941 (CDK2) | Uniprot |
| S440 | Phosphorylation | P24941 (CDK2) | Uniprot |
| T453 | Phosphorylation | Uniprot | |
| T458 | Phosphorylation | Uniprot | |
| T459 | Phosphorylation | Uniprot | |
| K460 | Ubiquitination | Uniprot | |
| Y483 | Phosphorylation | Uniprot | |
| S496 | Phosphorylation | Uniprot | |
| T505 | Phosphorylation | Uniprot | |
| K508 | Ubiquitination | Uniprot | |
| T519 | Phosphorylation | Uniprot | |
| K522 | Ubiquitination | Uniprot | |
| K531 | Acetylation | Uniprot | |
| T534 | Phosphorylation | Uniprot | |
| K539 | Ubiquitination | Uniprot | |
| T540 | Phosphorylation | Uniprot | |
| S548 | Phosphorylation | Uniprot | |
| R551 | Methylation | Uniprot | |
| K559 | Acetylation | Uniprot | |
| K559 | Methylation | Uniprot | |
| K559 | Ubiquitination | Uniprot | |
| Y562 | Phosphorylation | Uniprot | |
| S587 | Phosphorylation | Uniprot | |
| K592 | Acetylation | Uniprot | |
| K611 | Ubiquitination | Uniprot | |
| T621 | Phosphorylation | Uniprot |
研究背景
May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins.
Nucleus.
Widely expressed.
Component of the nucleosome-remodeling and histone-deacetylase multiprotein complex (NuRD) (By similarity). Interacts with HDAC7 and MBD3 (By similarity). Interacts with p53/TP53. Interacts with MINT. Interacts with PIMREG. Interacts with NACC2. Interacts with ERCC6.
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