| 产品: | hair cortex Cytokeratin 抗体 |
| 货号: | DF13328 |
| 描述: | Rabbit polyclonal antibody to hair cortex Cytokeratin |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Dog |
| 分子量: | 48kDa; 48kD(Calculated). |
| 蛋白号: | Q6A162 |
| RRID: | AB_2846347 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF13328, RRID:AB_2846347.
展开/折叠
CK-40; Cytokeratin-40; hair cortex Cytokeratin; K1C40_HUMAN; K40; Keratin; Keratin, type I cytoskeletal 40; Keratin-40; Krt40; type I cytoskeletal 40; Type I hair keratin Ka36;
抗原和靶标
Expressed in skin and scalp. Also very weakly expressed in tongue, breast, colon and small intestine. In the hair follicle, it is specifically present in the upper hair cuticle. Not present in the upper cortex (at protein level).
- Q6A162 K1C40_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTSDCSSTHCSPESCGTASGCAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLLPCYFTGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSPCSTTCTSSNTCEPCSAYVICTVENCCL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q6A162 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y103 | Phosphorylation | Uniprot | |
| T311 | Phosphorylation | Uniprot | |
| S313 | Phosphorylation | Uniprot |
研究背景
May play a role in late hair differentiation.
Expressed in skin and scalp. Also very weakly expressed in tongue, breast, colon and small intestine. In the hair follicle, it is specifically present in the upper hair cuticle. Not present in the upper cortex (at protein level).
Heterotetramer of two type I and two type II keratins.
Belongs to the intermediate filament family.
研究领域
· Organismal Systems > Endocrine system > Estrogen signaling pathway. (View pathway)
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