PGAM5 Antibody - #DF13355

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产品: PGAM5 抗体
货号: DF13355
描述: Rabbit polyclonal antibody to PGAM5
应用: WB IHC
文献验证: WB
反应: Human, Mouse, Rat
预测: Bovine, Horse, Sheep, Rabbit, Dog, Chicken
蛋白号: Q96HS1
RRID: AB_2846374

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
PGAM5 Antibody detects endogenous levels of total PGAM5.
RRID:
AB_2846374
引用格式: Affinity Biosciences Cat# DF13355, RRID:AB_2846374.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

Bcl-XL-binding protein v68; BXLBv68; MGC5352; mitochondrial; PGAM5; PGAM5_HUMAN; Phosphoglycerate mutase family member 5; Serine/threonine protein phosphatase PGAM5 mitochondrial; Serine/threonine-protein phosphatase PGAM5;

抗原和靶标

免疫原:

A synthesized peptide derived from human PGAM5, corresponding to a region within the internal amino acids.

基因/基因ID:
PGAM5(192111)

研究领域

· Cellular Processes > Cell growth and death > Necroptosis.   (View pathway)

· Environmental Information Processing > Signal transduction > TNF signaling pathway.   (View pathway)

文献引用

1). Pterocephin A, a Novel Triterpenoid Saponin from Pterocephalus hookeri Induced Liver Injury by Activation of Necroptosis. PHYTOMEDICINE, 2021 (PubMed: 33831690) [IF=6.7]

Application: WB    Species: Human    Sample: L-02 cells

Fig 4. PA activated RIP1 signaling pathway. A. Western blot analysis for RIP1 signaling pathway in L-02 cells with PA treatment; B. Western blot analysis for RIP1 signaling pathway with the interference of Nec-1 in L-02 cells. For A: Data were represented as mean ± SD (n = 3), * p < 0.05, ** p < 0.01 compared with the Con group. For B: Data were represented as mean ± SD (n = 3); # p < 0.05, ## p < 0.01 compared with the Con group; * p < 0.05, ** p < 0.01 compared with the PA- 4 group.
2). ZBP1 promotes hepatocyte pyroptosis in acute liver injury by regulating the PGAM5/ROS pathway. Annals of hepatology, 2024 (PubMed: 38331384) [IF=3.7]
3). Vascular endothelial cell damage induced by ox-LDL through AMPK-Nrf2/Keap1-PGAM5 signaling axis. Research Square, 2022

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