产品: PF4 抗体
货号: DF13361
描述: Rabbit polyclonal antibody to PF4
应用: WB IHC IF/ICC
反应: Human, Mouse, Rat
预测: Pig
分子量: 10kDa; 11kD(Calculated).
蛋白号: P02776
RRID: AB_2846380

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
IF/ICC 1:100-1:500, WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
预测:
Pig(86%)
克隆:
Polyclonal
特异性:
PF4 Antibody detects endogenous levels of total PF4.
RRID:
AB_2846380
引用格式: Affinity Biosciences Cat# DF13361, RRID:AB_2846380.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

C-X-C motif chemokine 4;Chemokine (C X C motif) ligand 4;Chemokine (CXC motif) ligand 4;chemokine ligand 4;CXCL 4;CXCL4;Iroplact;MGC138298;Oncostatin A;Oncostatin-A;OncostatinA;PF 4;PF-4;PF4;Pf4a;Platelet factor 4;PLF4_HUMAN;SCYB 4;SCYB4;short form;Small inducible cytokine subfamily B;Small inducible cytokine subfamily member 4 antibody

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
序列:
MSSAAGFCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
86
Bovine
71
Sheep
71
Horse
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

功能:

Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.

细胞定位:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
亚基结构:

Homotetramer.

蛋白家族:

Belongs to the intercrine alpha (chemokine CxC) family.

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Organismal Systems > Immune system > Chemokine signaling pathway.   (View pathway)

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