| 产品: | HBZ 抗体 |
| 货号: | DF13400 |
| 描述: | Rabbit polyclonal antibody to HBZ |
| 应用: | WB IHC |
| 反应: | Human |
| 预测: | Pig, Bovine |
| 分子量: | 15kDa; 16kD(Calculated). |
| 蛋白号: | P02008 |
| RRID: | AB_2846419 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF13400, RRID:AB_2846419.
展开/折叠
HBAZ; HBAZ_HUMAN; HBZ 2; HBZ; HBZ2; Hemoglobin subunit zeta; Hemoglobin zeta; Hemoglobin zeta chain; Zeta globin; Zeta-globin;
抗原和靶标
- P02008 HBAZ_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHFDLHPGSAQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTAEAHAAWDKFLSVVSSVLTEKYR
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P02008 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| K5 | Acetylation | Uniprot | |
| T24 | Phosphorylation | Uniprot | |
| T29 | Phosphorylation | Uniprot | |
| S36 | Phosphorylation | Uniprot | |
| T40 | Phosphorylation | Uniprot | |
| K41 | Acetylation | Uniprot | |
| K41 | Ubiquitination | Uniprot | |
| Y43 | Phosphorylation | Uniprot | |
| S53 | Phosphorylation | Uniprot | |
| K62 | Ubiquitination | Uniprot | |
| S73 | Phosphorylation | Uniprot | |
| S82 | Phosphorylation | Uniprot | |
| K83 | Acetylation | Uniprot | |
| K83 | Ubiquitination | Uniprot | |
| Y90 | Phosphorylation | Uniprot | |
| K100 | Acetylation | Uniprot |
研究背景
The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin.
Detected in fetal erythrocytes (at protein level).
Heterotetramer of two zeta chains and two epsilon chains in early embryonic hemoglobin Gower-1; two zeta chains and two gamma chains in fetal hemoglobin Portland-1. Heterotetramer of two zeta chains and two beta chains in hemoglobin Portland-2, detected in fetuses and neonates with homozygous alpha-thalassemia.
Belongs to the globin family.
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