| 产品: | Natriuretic Peptide Receptor C 抗体 |
| 货号: | DF13434 |
| 描述: | Rabbit polyclonal antibody to Natriuretic Peptide Receptor C |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 59kDa; 60kD(Calculated). |
| 蛋白号: | P17342 |
| RRID: | AB_2846453 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF13434, RRID:AB_2846453.
展开/折叠
ANP C; ANP-C; ANPC; ANPR-C; ANPRC; ANPRC_HUMAN; Atrial natriuretic peptide C type receptor; Atrial natriuretic peptide clearance receptor; Atrial natriuretic peptide receptor 3; Atrial natriuretic peptide receptor type C; Atrionatriuretic peptide receptor C; C5orf23; FLJ14054; GUCY2B; MGC22189; Natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C); Natriuretic peptide receptor C/guanylate cyclase C; NPR 3; NPR C; NPR-C; Npr3; NPRC;
抗原和靶标
- P17342 ANPRC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLPQDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSSGGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSVA
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P17342 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N86 | N-Glycosylation | Uniprot | |
| S148 | Phosphorylation | Uniprot | |
| S156 | Phosphorylation | Uniprot | |
| N293 | N-Glycosylation | Uniprot | |
| Y316 | Phosphorylation | Uniprot | |
| N394 | N-Glycosylation | Uniprot | |
| Y502 | Phosphorylation | Uniprot | |
| K525 | Ubiquitination | Uniprot | |
| S533 | Phosphorylation | Uniprot |
研究背景
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
Membrane>Single-pass type I membrane protein.
Homodimer; disulfide-linked. Dimers can also be formed through the C-terminal cysteine of isoform 2. Interacts with OSTN (By similarity).
Belongs to the ANF receptor family.
限制条款
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