IL1RAP Antibody - #DF13533

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产品: IL1RAP 抗体
货号: DF13533
描述: Rabbit polyclonal antibody to IL1RAP
应用: WB
文献验证: WB
反应: Human, Mouse, Rat
预测: Horse, Sheep, Rabbit, Dog, Chicken
蛋白号: Q9NPH3
RRID: AB_2846552

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat
克隆:
Polyclonal
特异性:
IL1RAP Antibody detects endogenous levels of total IL1RAP.
RRID:
AB_2846552
引用格式: Affinity Biosciences Cat# DF13533, RRID:AB_2846552.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

C3orf13; FLJ37788; IL 1 receptor accessory protein; IL 1R 3; IL 1R3; IL 1RAcP; IL 1RAP; IL-1 receptor accessory protein; IL-1R-3; IL-1R3; IL-1RAcP; IL-1RAP; IL1 receptor accessory protein; IL1AP_HUMAN; IL1R3; IL1RAcP; Il1rap; Interleukin 1 Accessory Protein; interleukin 1 receptor 3; Interleukin 1 receptor accessory protein; interleukin 1 receptor accessory protein beta; Interleukin-1 receptor 3; Interleukin-1 receptor accessory protein;

抗原和靶标

免疫原:

A synthesized peptide derived from human IL1RAP, corresponding to a region within C-terminal amino acids.

基因/基因ID:
IL1RAP(3556)

研究领域

· Environmental Information Processing > Signal transduction > MAPK signaling pathway.   (View pathway)

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Organismal Systems > Immune system > Th17 cell differentiation.   (View pathway)

· Organismal Systems > Sensory system > Inflammatory mediator regulation of TRP channels.   (View pathway)

文献引用

1). Circ_0007611 stimulates IL-1 receptor accessory protein to inhibit trophoblast cell proliferation and induce cell apoptosis. BIOLOGY OF REPRODUCTION, 2022 (PubMed: 35238896) [IF=3.1]

Application: WB    Species: Human    Sample: placental tissues

Figure 5 Circ_0007611 mediated IL1RAP expression through miR-558. (A) The binding sites of miR-558 and IL1RAP. (B) The interaction between miR-558 and IL1RAP was identified by a dual-luciferase reporter assay. (C and D) The effects of miR-558 mimics and inhibitors on IL1RAP protein expression were determined by Western blot. (E–G) IL1RAP expression was detected by qRT-PCR and Western blot in placental tissues of PE women and normal placental tissues. (H and I) Spearman correlation analysis was implemented to analyze the correlation between IL1RAP and miR-558 or circ_0007611 expression in the placental tissues of PE women. (J and K) The effects of circ_0007611 and miR-558 on IL1RAP protein expression were testified by Western blot analysis. IL-1 receptor accessory protein (IL1RAP); wild-type (WT); mutant (MUT); 3′-untranslated region (3’UTR); IL-1 receptor accessory protein (IL1RAP); microRNA-558 (miR-558); normal pregnant women (NP); preeclampsia (PE); circRNA 0007611 (circ_0007611); GAPDH.

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