| 产品: | GP210 抗体 |
| 货号: | DF13536 |
| 描述: | Rabbit polyclonal antibody to GP210 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Horse, Rabbit, Dog |
| 分子量: | 205kDa; 205kD(Calculated). |
| 蛋白号: | Q8TEM1 |
| RRID: | AB_2846555 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF13536, RRID:AB_2846555.
展开/折叠
FLJ22389; GP 210; KIAA0906; Nuclear envelope pore membrane protein POM 210; Nuclear pore membrane glycoprotein 210; Nuclear pore protein gp210; Nucleoporin 210; Nucleoporin 210kDa; Nucleoporin Nup210; Nucleoporin210; NUP 210; Nup210; PO210_HUMAN; POM 210; POM210; Pore membrane protein of 210 kDa;
抗原和靶标
Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle.
- Q8TEM1 PO210_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAARGRGLLLLTLSVLLAAGPSAAAAKLNIPKVLLPFTRATRVNFTLEASEGCYRWLSTRPEVASIEPLGLDEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHDIQIVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFEWTIVKDSEADRFSDSHNALRILTFLESTYIPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLILENILLNPAYDVYLMVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPGPEGDPARPVAVLAQDTSMVTALQLGQSSLVLGHRSIRMQGASRLPNSTIYVVEPGYLGFTVHPGDRWVLETGRLYEITIEVFDKFSNKVYVSDNIRIETVLPAEFFEVLSSSQNGSYHRIRALKRGQTAIDAALTSVVDQDGGVHILQVPVWNQQEVEIHIPITLYPSILTFPWQPKTGAYQYTIRAHGGSGNFSWSSSSHLVATVTVKGVMTTGSDIGFSVIQAHDVQNPLHFGEMKVYVIEPHSMEFAPCQVEARVGQALELPLRISGLMPGGASEVVTLSDCSHFDLAVEVENQGVFQPLPGRLPPGSEHCSGIRVKAEAQGSTTLLVSYRHGHVHLSAKITIAAYLPLKAVDPSSVALVTLGSSKEMLFEGGPRPWILEPSKFFQNVTAEDTDSIGLALFAPHSSRNYQQHWILVTCQALGEQVIALSVGNKPSLTNPFPAVEPAVVKFVCAPPSRLTLAPVYTSPQLDMSCPLLQQNKQVVPVSSHRNPRLDLAAYDQEGRRFDNFSSLSIQWESTRPVLASIEPELPMQLVSQDDESGQKKLHGLQAILVHEASGTTAITATATGYQESHLSSARTKQPHDPLVPLSASIELILVEDVRVSPEEVTIYNHPGIQAELRIREGSGYFFLNTSTADVVKVAYQEARGVAMVHPLLPGSSTIMIHDLCLVFPAPAKAVVYVSDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLKLRAASPIITLVALDEALDNYTITFLIRGVAIGQTSLTASVTNKAGQRINSAPQQIEVFPPFRLMPRKVTLLIGATMQVTSEGGPQPQSNILFSISNESVALVSAAGLVQGLAIGNGTVSGLVQAVDAETGKVVIISQDLVQVEVLLLRAVRIRAPIMRMRTGTQMPIYVTGITNHQNPFSFGNAVPGLTFHWSVTKRDVLDLRGRHHEASIRLPSQYNFAMNVLGRVKGRTGLRVVVKAVDPTSGQLYGLARELSDEIQVQVFEKLQLLNPEIEAEQILMSPNSYIKLQTNRDGAASLSYRVLDGPEKVPVVHVDEKGFLASGSMIGTSTIEVIAQEPFGANQTIIVAVKVSPVSYLRVSMSPVLHTQNKEALVAVPLGMTVTFTVHFHDNSGDVFHAHSSVLNFATNRDDFVQIGKGPTNNTCVVRTVSVGLTLLRVWDAEHPGLSDFMPLPVLQAISPELSGAMVVGDVLCLATVLTSLEGLSGTWSSSANSILHIDPKTGVAVARAVGSVTVYYEVAGHLRTYKEVVVSVPQRIMARHLHPIQTSFQEATASKVIVAVGDRSSNLRGECTPTQREVIQALHPETLISCQSQFKPAVFDFPSQDVFTVEPQFDTALGQYFCSITMHRLTDKQRKHLSMKKTALVVSASLSSSHFSTEQVGAEVPFSPGLFADQAEILLSNHYTSSEIRVFGAPEVLENLEVKSGSPAVLAFAKEKSFGWPSFITYTVGVLDPAAGSQGPLSTTLTFSSPVTNQAIAIPVTVAFVVDRRGPGPYGASLFQHFLDSYQVMFFTLFALLAGTAVMIIAYHTVCTPRDLAVPAALTPRASPGHSPHYFAASSPTSPNALPPARKASPPSGLWSPAYASH
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q8TEM1 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K32 | Ubiquitination | Uniprot | |
| K79 | Ubiquitination | Uniprot | |
| Y129 | Phosphorylation | Uniprot | |
| R169 | Methylation | Uniprot | |
| S171 | Phosphorylation | Uniprot | |
| S194 | Phosphorylation | Uniprot | |
| K201 | Ubiquitination | Uniprot | |
| T205 | Phosphorylation | Uniprot | |
| S209 | Phosphorylation | Uniprot | |
| K212 | Ubiquitination | Uniprot | |
| K228 | Ubiquitination | Uniprot | |
| K379 | Ubiquitination | Uniprot | |
| N405 | N-Glycosylation | Uniprot | |
| T504 | Phosphorylation | Uniprot | |
| T505 | Phosphorylation | Uniprot | |
| K660 | Ubiquitination | Uniprot | |
| K774 | Ubiquitination | Uniprot | |
| N926 | N-Glycosylation | Uniprot | |
| Y937 | Phosphorylation | Uniprot | |
| K988 | Ubiquitination | Uniprot | |
| K993 | Ubiquitination | Uniprot | |
| T994 | Phosphorylation | Uniprot | |
| Y998 | Phosphorylation | Uniprot | |
| K1020 | Ubiquitination | Uniprot | |
| K1063 | Ubiquitination | Uniprot | |
| R1223 | Methylation | Uniprot | |
| R1246 | Methylation | Uniprot | |
| K1258 | Ubiquitination | Uniprot | |
| Y1268 | Phosphorylation | Uniprot | |
| S1301 | Phosphorylation | Uniprot | |
| S1304 | Phosphorylation | Uniprot | |
| Y1305 | Phosphorylation | Uniprot | |
| T1310 | Phosphorylation | Uniprot | |
| S1319 | Phosphorylation | Uniprot | |
| K1328 | Ubiquitination | Uniprot | |
| T1350 | Phosphorylation | Uniprot | |
| S1380 | Phosphorylation | Uniprot | |
| K1437 | Ubiquitination | Uniprot | |
| N1441 | N-Glycosylation | Uniprot | |
| K1547 | Ubiquitination | Uniprot | |
| K1576 | Ubiquitination | Uniprot | |
| R1584 | Methylation | Uniprot | |
| R1589 | Methylation | Uniprot | |
| K1724 | Ubiquitination | Uniprot | |
| S1725 | Phosphorylation | Uniprot | |
| S1727 | Phosphorylation | Uniprot | |
| K1735 | Ubiquitination | Uniprot | |
| T1844 | Phosphorylation | Uniprot | |
| S1848 | Phosphorylation | Uniprot | |
| S1852 | Phosphorylation | Uniprot | |
| Y1855 | Phosphorylation | Uniprot | |
| S1859 | Phosphorylation | Uniprot | |
| S1860 | Phosphorylation | Uniprot | |
| T1862 | Phosphorylation | Uniprot | |
| S1863 | Phosphorylation | Uniprot | |
| K1872 | Ubiquitination | Uniprot | |
| S1874 | Phosphorylation | Uniprot | |
| S1877 | Phosphorylation | Uniprot | |
| S1881 | Phosphorylation | Uniprot | |
| Y1884 | Phosphorylation | Uniprot | |
| S1886 | Phosphorylation | Uniprot |
研究背景
Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity.
N-glycosylated, but not all potential glycosylation sites may be used. Contains high-mannose type oligosaccharides (By similarity).
Phosphorylated at Ser-1881 in mitosis specifically; not phosphorylated in interphase.
Nucleus>Nuclear pore complex. Nucleus membrane>Single-pass type I membrane protein. Endoplasmic reticulum membrane>Single-pass type I membrane protein.
Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle.
Forms dimers and possibly higher-order oligomers.
Belongs to the NUP210 family.
研究领域
· Genetic Information Processing > Translation > RNA transport.
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