| 产品: | Ornithine Carbamoyltransferase 抗体 |
| 货号: | DF13552 |
| 描述: | Rabbit polyclonal antibody to Ornithine Carbamoyltransferase |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 39kDa, 55 kDa; 40kD(Calculated). |
| 蛋白号: | P00480 |
| RRID: | AB_2846571 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF13552, RRID:AB_2846571.
展开/折叠
EC 2.1.3.3; MGC129967; MGC129968; MGC138856; OCTD; Ornithine Carbamoyltransferase; Ornithine carbamoyltransferase mitochondrial; Ornithine carbamoyltransferase, mitochondrial; Ornithine transcarbamylase; Otc; OTC_HUMAN; OTCase;
抗原和靶标
- P00480 OTC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLFNLRILLNNAAFRNGHNFMVRNFRCGQPLQNKVQLKGRDLLTLKNFTGEEIKYMLWLSADLKFRIKQKGEYLPLLQGKSLGMIFEKRSTRTRLSTETGFALLGGHPCFLTTQDIHLGVNESLTDTARVLSSMADAVLARVYKQSDLDTLAKEASIPIINGLSDLYHPIQILADYLTLQEHYSSLKGLTLSWIGDGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKKKRLQAFQGYQVTMKTAKVAASDWTFLHCLPRKPEEVDDEVFYSPRSLVFPEAENRKWTIMAVMVSLLTDYSPQLQKPKF
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P00480 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K46 | Acetylation | Uniprot | |
| Y55 | Phosphorylation | Uniprot | |
| K88 | Acetylation | Uniprot | |
| S133 | Phosphorylation | Uniprot | |
| S146 | Phosphorylation | Uniprot | |
| Y223 | Phosphorylation | Uniprot | |
| K231 | Acetylation | Uniprot | |
| Y284 | Phosphorylation | Uniprot | |
| Y317 | Phosphorylation | Uniprot |
研究背景
Acetylation at Lys-88 negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals.
Mitochondrion matrix.
Mainly expressed in liver and intestinal mucosa.
Homotrimer.
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
研究领域
· Metabolism > Amino acid metabolism > Arginine biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Biosynthesis of amino acids.
限制条款
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