Surfactant protein D Antibody - #DF13601
产品: | Surfactant protein D 抗体 |
货号: | DF13601 |
描述: | Rabbit polyclonal antibody to Surfactant protein D |
应用: | WB IF/ICC |
反应: | Human, Mouse, Rat |
预测: | Bovine, Horse, Sheep, Rabbit, Dog |
分子量: | 38kDa; 38kD(Calculated). |
蛋白号: | P35247 |
RRID: | AB_2846620 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF13601, RRID:AB_2846620.
展开/折叠
COLEC 7; COLEC7; Collectin-7; Collectin7; Lung surfactant protein D; PSP D; PSP-D; PSP-D Surfactant protein D; PSPD; Pulmonary surfactant apoprotein; Pulmonary surfactant associated protein D; Pulmonary surfactant associated protein PSP-D; Pulmonary surfactant-associated protein D; SFTP 4; SFTP4; SFTPD; SFTPD_HUMAN; SP D; SP-D; Surfactant associated protein pulmonary 4; Surfactant protein D; Surfactant pulmonary associated protein D;
抗原和靶标
Expressed in lung, brain, pancreas and adipose tissue (mainly mature adipocytes).
- P35247 SFTPD_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLLFLLSALVLLTQPLGYLEAEMKTYSHRTMPSACTLVMCSSVESGLPGRDGRDGREGPRGEKGDPGLPGAAGQAGMPGQAGPVGPKGDNGSVGEPGPKGDTGPSGPPGPPGVPGPAGREGPLGKQGNIGPQGKPGPKGEAGPKGEVGAPGMQGSAGARGLAGPKGERGVPGERGVPGNTGAAGSAGAMGPQGSPGARGPPGLKGDKGIPGDKGAKGESGLPDVASLRQQVEALQGQVQHLQAAFSQYKKVELFPNGQSVGEKIFKTAGFVKPFTEAQLLCTQAGGQLASPRSAAENAALQQLVVAKNEAAFLSMTDSKTEGKFTYPTGESLVYSNWAPGEPNDDGGSEDCVEIFTNGKWNDRACGEKRLVVCEF
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P35247 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T30 | Phosphorylation | Uniprot | |
S33 | Phosphorylation | Uniprot | |
C35 | S-Nitrosylation | Uniprot | |
C40 | S-Nitrosylation | Uniprot |
研究背景
Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
The N-terminus is blocked.
Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates.
S-nitrosylation at Cys-35 and Cys-40 alters the quaternary structure which results in a pro-inflammatory chemoattractive signaling activity with macrophages.
Secreted>Extracellular space>Extracellular matrix. Secreted>Extracellular space>Surface film.
Expressed in lung, brain, pancreas and adipose tissue (mainly mature adipocytes).
Oligomeric complex of 4 set of homotrimers.
Belongs to the SFTPD family.
研究领域
· Cellular Processes > Transport and catabolism > Phagosome. (View pathway)
文献引用
Application: WB Species: Mouse Sample: lung tissue
限制条款
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