| 产品: | KC1AL 抗体 |
| 货号: | DF13605 |
| 描述: | Rabbit polyclonal antibody to KC1AL |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 分子量: | 40kDa, 33 kDa; 39kD(Calculated). |
| 蛋白号: | Q8N752 |
| RRID: | AB_2846624 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF13605, RRID:AB_2846624.
展开/折叠
Casein kinase 1, alpha 1 like; casein kinase 1, alpha 1-like; Casein kinase I alpha S like; Casein kinase I isoform alpha like; CK1; CKI alpha like; MGC33182; OTTHUMP00000018267; RP11 532O21.2;
抗原和靶标
- Q8N752 KC1AL_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYESKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN
翻译修饰 - Q8N752 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K53 | Acetylation | Uniprot | |
| Y59 | Phosphorylation | Uniprot | |
| K62 | Acetylation | Uniprot | |
| K83 | Acetylation | Uniprot | |
| K130 | Ubiquitination | Uniprot | |
| T146 | Phosphorylation | Uniprot | |
| K152 | Ubiquitination | Uniprot | |
| K162 | Ubiquitination | Uniprot | |
| T184 | Phosphorylation | Uniprot | |
| S206 | Phosphorylation | Uniprot | |
| Y209 | Phosphorylation | Uniprot | |
| Y213 | Phosphorylation | Uniprot | |
| K240 | Ubiquitination | Uniprot | |
| T287 | Phosphorylation | Uniprot | |
| Y292 | Phosphorylation | Uniprot | |
| Y294 | Phosphorylation | Uniprot | |
| K302 | Ubiquitination | Uniprot |
研究背景
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity).
Cytoplasm.
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
研究领域
· Environmental Information Processing > Signal transduction > Wnt signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Hedgehog signaling pathway. (View pathway)
· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.
· Human Diseases > Cancers: Specific types > Breast cancer. (View pathway)
· Human Diseases > Cancers: Specific types > Hepatocellular carcinoma. (View pathway)
· Human Diseases > Cancers: Specific types > Gastric cancer. (View pathway)
限制条款
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