产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF13618, RRID:AB_2846637.
展开/折叠
BN; Gastric releasing peptide; Gastrin releasing peptide; GRP 10; GRP; GRP10; Neuromedin C; NeuromedinC; Pre progastrin releasing peptide; PreproGRP; ProGRP;
抗原和靶标
- P07492 GRP_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRGRELPLVLLALVLCLAPRGRAVPLPAGGGTVLTKMYPRGNHWAVGHLMGKKSTGESSSVSERGSLKQQLREYIRWEEAARNLLGLIEAKENRNHQPPQPKALGNQQPSWDSEDSSNFKDVGSKGKVGRLSAPGSQREGRNPQLNQQ
种属预测
score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P07492 作为底物
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T32 | Phosphorylation | Uniprot | |
K52 | Ubiquitination | Uniprot | |
K53 | Ubiquitination | Uniprot | |
K68 | Acetylation | Uniprot | |
K127 | Acetylation | Uniprot |
研究背景
Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake (By similarity).
Secreted. Cytoplasmic vesicle>Secretory vesicle lumen.
Belongs to the bombesin/neuromedin-B/ranatensin family.
限制条款
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