| 产品: | TBKBP1 抗体 |
| 货号: | DF13686 |
| 描述: | Rabbit polyclonal antibody to TBKBP1 |
| 应用: | WB |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 67kDa; 68kD(Calculated). |
| 蛋白号: | A7MCY6 |
| RRID: | AB_2846705 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF13686, RRID:AB_2846705.
展开/折叠
KIAA0775; ProSAPiP2; SINTBAD; TANK binding kinase 1 binding protein 1; TANK-binding kinase 1-binding protein 1; TBK1 binding protein 1; TBK1-binding protein 1; TBKB1_HUMAN; Tbkbp1;
抗原和靶标
Detected in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, muscle, heart, brain and at low levels in thymus.
- A7MCY6 TBKB1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MESMFEDDISILTQEALGPSEVWLDSPGDPSLGGDMCSASHFALITAYGDIKERLGGLERENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQKNKEQEEQLGEMIQAYEKLCVEKSDLETELREMRALVETHLRQICGLEQQLRQQQGLQDAAFSNLSPPPAPAPPCTDLDLHYLALRGGSGLSHAGWPGSTPSVSDLERRRLEEALEAAQGEARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAYTELTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAPQPRPPPPPPPGERTLAERAYAKPPSHHVKAGFQGRRSYSELAEGAAYAGASPPWLQAEAATLPKPRAYGSELYGPGRPLSPRRAFEGIRLRFEKQPSEEDEWAVPTSPPSPEVGTIRCASFCAGFPIPESPAATAYAHAEHAQSWPSINLLMETVGSDIRSCPLCQLGFPVGYPDDALIKHIDSHLENSKI
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - A7MCY6 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S10 | Phosphorylation | Uniprot | |
| T13 | Phosphorylation | Uniprot | |
| Y48 | Phosphorylation | Uniprot | |
| K70 | Ubiquitination | Uniprot | |
| S97 | Phosphorylation | Uniprot | |
| K103 | Ubiquitination | Uniprot | |
| S105 | Phosphorylation | Uniprot | |
| K119 | Ubiquitination | Uniprot | |
| K121 | Ubiquitination | Uniprot | |
| S184 | Phosphorylation | Uniprot | |
| K262 | Ubiquitination | Uniprot | |
| K285 | Ubiquitination | Uniprot | |
| S335 | Phosphorylation | Uniprot | |
| S349 | Phosphorylation | Uniprot | |
| S351 | Phosphorylation | Uniprot | |
| S365 | Phosphorylation | Uniprot | |
| S372 | Phosphorylation | Uniprot | |
| S379 | Phosphorylation | Uniprot | |
| S385 | Phosphorylation | Uniprot | |
| S388 | Phosphorylation | Uniprot | |
| S390 | Phosphorylation | Uniprot | |
| S393 | Phosphorylation | Uniprot | |
| S400 | Phosphorylation | Uniprot | |
| S405 | Phosphorylation | Uniprot | |
| S415 | Phosphorylation | Uniprot | |
| T485 | Phosphorylation | Uniprot | |
| S504 | Phosphorylation | Uniprot | |
| R513 | Methylation | Uniprot | |
| S521 | Phosphorylation | Uniprot | |
| S534 | Phosphorylation | Uniprot |
研究背景
Adapter protein which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.
Detected in leukocytes, lung, placenta, small intestine, liver, kidney, spleen, muscle, heart, brain and at low levels in thymus.
Homodimer. May form a heterodimer with NAP1. Interacts with TKB1 and IKBKE.
(Microbial infection) Interacts with vaccinia virus protein C6.
研究领域
· Organismal Systems > Immune system > RIG-I-like receptor signaling pathway. (View pathway)
限制条款
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