产品描述
来源:
Rabbit
应用:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
反应:
Human,Mouse,Rat
预测:
Pig(88%), Bovine(88%), Horse(88%), Sheep(88%)
克隆:
Polyclonal
特异性:
KIAA0701 Antibody detects endogenous levels of total KIAA0701.
RRID:
AB_2846710
引用格式: Affinity Biosciences Cat# DF13691, RRID:AB_2846710.
引用格式: Affinity Biosciences Cat# DF13691, RRID:AB_2846710.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:
展开/折叠
Hypothetical protein LOC23074; UH1BL_HUMAN; UHRF1 binding protein 1 like; UHRF1-binding protein 1-like; UHRF1BP1L; KIAA0701;
抗原和靶标
免疫原:
Uniprot:
基因/基因ID:
序列:
- A0JNW5 UH1BL_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAINKVFCNKASIRIPWTKLKTHPICLSLDKVIMEMSTCEEPRSPNGPSPIATASGQSEYGFAEKVVEGISVSVNSIVIRIGAKAFNASFELSQLRIYSVNAHWEHGDLRFTRIQDPQRGEVLTFKEINWQMIRIEADATQSSHLEIMCAPVRLITNQSKIRVTLKRRLKDCNVIATKLVLILDDLLWVLTDSQLKAMVQYAKSLSEAIEKSTEQRKSMAPEPTQSSTVVASAQQVKTTQTSNAPDVNDAIVKLFNDFDVKETSHHLVISHLDLHICDDIHAKEKESNRRITGGAMQLSFTQLTIDYYPYHKAGDSCNHWMYFSDATKTKNGWANELLHEFECNVEMLKQAVKDHNVGSPPKSPTHASPQHTQTEKDYPLKGTCRTPSVLSQQSKAKLMSSSVVVRLADFNIYQVSTAEQCRSSPKSMICCNKKSLYLPQEMSAVYIEFTEYYYPDGKDFPIPSPNLYSQLNALQFTVDERSILWLNQFLLDLKQSLNQFMAVYKLNDNSKSDEHVDVRVDGLMLKFVIPSEVKSECHQDQPRAISIQSSEMIATNTRHCPNCRHSDLEALFQDFKDCDFFSKTYTSFPKSCDNFNLLHPIFQRHAHEQDTKMHEIYKGNITPQLNKNTLKTSAATDVWAVYFSQFWIDYEGMKSGKGRPISFVDSFPLSIWICQPTRYAESQKEPQTCNQVSLNTSQSESSDLAGRLKRKKLLKEYYSTESEPLTNGGQKPSSSDTFFRFSPSSSEADIHLLVHVHKHVSMQINHYQYLLLLFLHESLILLSENLRKDVEAVTGSPASQTSICIGILLRSAELALLLHPVDQANTLKSPVSESVSPVVPDYLPTENGDFLSSKRKQISRDINRIRSVTVNHMSDNRSMSVDLSHIPLKDPLLFKSASDTNLQKGISFMDYLSDKHLGKISEDESSGLVYKSGSGEIGSETSDKKDSFYTDSSSILNYREDSNILSFDSDGNQNILSSTLTSKGNETIESIFKAEDLLPEAASLSENLDISKEETPPVRTLKSQSSLSGKPKERCPPNLAPLCVSYKNMKRSSSQMSLDTISLDSMILEEQLLESDGSDSHMFLEKGNKKNSTTNYRGTAESVNAGANLQNYGETSPDAISTNSEGAQENHDDLMSVVVFKITGVNGEIDIRGEDTEICLQVNQVTPDQLGNISLRHYLCNRPVGSDQKAVIHSKSSPEISLRFESGPGAVIHSLLAEKNGFLQCHIENFSTEFLTSSLMNIQHFLEDETVATVMPMKIQVSNTKINLKDDSPRSSTVSLEPAPVTVHIDHLVVERSDDGSFHIRDSHMLNTGNDLKENVKSDSVLLTSGKYDLKKQRSVTQATQTSPGVPWPSQSANFPEFSFDFTREQLMEENESLKQELAKAKMALAEAHLEKDALLHHIKKMTVE
种属预测
种属预测:
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
Species
Results
Score
Pig
88
Horse
88
Bovine
88
Sheep
88
Dog
75
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - A0JNW5 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K6 | Acetylation | Uniprot | |
| S14 | Phosphorylation | Uniprot | |
| K24 | Ubiquitination | Uniprot | |
| S67 | Phosphorylation | Uniprot | |
| T73 | Phosphorylation | Uniprot | |
| S126 | Phosphorylation | Uniprot | |
| S131 | Phosphorylation | Uniprot | |
| S259 | Phosphorylation | Uniprot | |
| S261 | Phosphorylation | Uniprot | |
| K266 | Ubiquitination | Uniprot | |
| K308 | Ubiquitination | Uniprot | |
| Y362 | Phosphorylation | Uniprot | |
| Y363 | Phosphorylation | Uniprot | |
| Y365 | Phosphorylation | Uniprot | |
| S414 | Phosphorylation | Uniprot | |
| S418 | Phosphorylation | Uniprot | |
| T420 | Phosphorylation | Uniprot | |
| S423 | Phosphorylation | Uniprot | |
| T427 | Phosphorylation | Uniprot | |
| T441 | Phosphorylation | Uniprot | |
| S443 | Phosphorylation | Uniprot | |
| S446 | Phosphorylation | Uniprot | |
| S449 | Phosphorylation | Uniprot | |
| K450 | Ubiquitination | Uniprot | |
| T612 | Phosphorylation | Uniprot | |
| T677 | Phosphorylation | Uniprot | |
| S754 | Phosphorylation | Uniprot | |
| Y772 | Phosphorylation | Uniprot | |
| Y773 | Phosphorylation | Uniprot | |
| S774 | Phosphorylation | Uniprot | |
| S889 | Phosphorylation | Uniprot | |
| S891 | Phosphorylation | Uniprot | |
| S933 | Phosphorylation | Uniprot | |
| S935 | Phosphorylation | Uniprot | |
| S939 | Phosphorylation | Uniprot | |
| K950 | Methylation | Uniprot | |
| S953 | Phosphorylation | Uniprot | |
| T955 | Phosphorylation | Uniprot | |
| S962 | Phosphorylation | Uniprot | |
| Y966 | Phosphorylation | Uniprot | |
| S968 | Phosphorylation | Uniprot | |
| S976 | Phosphorylation | Uniprot | |
| Y985 | Phosphorylation | Uniprot | |
| K986 | Ubiquitination | Uniprot | |
| S987 | Phosphorylation | Uniprot | |
| S989 | Phosphorylation | Uniprot | |
| S1058 | Phosphorylation | Uniprot | |
| S1060 | Phosphorylation | Uniprot | |
| S1066 | Phosphorylation | Uniprot | |
| T1070 | Phosphorylation | Uniprot | |
| K1077 | Methylation | Uniprot | |
| S1078 | Phosphorylation | Uniprot | |
| S1081 | Phosphorylation | Uniprot | |
| Y1101 | Phosphorylation | Uniprot | |
| S1107 | Phosphorylation | Uniprot | |
| S1108 | Phosphorylation | Uniprot | |
| S1109 | Phosphorylation | Uniprot | |
| K1244 | Ubiquitination | Uniprot | |
| S1252 | Phosphorylation | Uniprot | |
| S1269 | Phosphorylation | Uniprot | |
| S1327 | Phosphorylation | Uniprot | |
| T1367 | Phosphorylation | Uniprot | |
| S1402 | Phosphorylation | Uniprot |
研究背景
细胞定位:
Cytoplasm>Cytosol. Early endosome.
Note: Primarily cytosolic. Recruited to early endosomes following STX6 overexpression. Overexpression of both STX6 and UHRF1BP1L results in aberrant tubulation of endosomal membranes.
亚基结构:
Monomer. Homodimer (via N-terminus). Associates with the Golgi-associated retrograde protein (GARP) complex. Interacts with GARP complex component VPS52. Interacts (via C-terminal coiled-coil domain) with STX6.
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