| 产品: | EEF1A2 抗体 |
| 货号: | AF6618 |
| 描述: | Rabbit polyclonal antibody to EEF1A2 |
| 应用: | ELISA(peptide) |
| 反应: | Human, Mouse, Rat |
| 分子量: | 50kD(Calculated). |
| 蛋白号: | Q05639 |
| RRID: | AB_2847341 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF6618, RRID:AB_2847341.
展开/折叠
eEF1A-2; Eef1a2; EEF1AL; EF 1 alpha 2; EF-1-alpha-2; EF1A; EF1A2_HUMAN; Elongation factor 1 A 2; Elongation factor 1 alpha; Elongation factor 1 alpha 2; Elongation factor 1-alpha 2; Eukaryotic elongation factor 1 A-2; Eukaryotic translation elongation factor 1 alpha 2; FLJ41696; HS1; OTTHUMP00000031776; Statin like; Statin S1; Statin-S1; STN; STNL;
抗原和靶标
A synthesized peptide derived from human EEF1A2.
- Q05639 EF1A2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK
翻译修饰 - Q05639 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S21 | Phosphorylation | P15056 (BRAF) , P04049 (RAF1) | Uniprot |
| T22 | Phosphorylation | Uniprot | |
| T23 | Phosphorylation | Uniprot | |
| T24 | Phosphorylation | Uniprot | |
| Y29 | Phosphorylation | Uniprot | |
| K30 | Acetylation | Uniprot | |
| K30 | Methylation | Uniprot | |
| K30 | Ubiquitination | Uniprot | |
| K36 | Acetylation | Uniprot | |
| K36 | Methylation | Uniprot | |
| K36 | Ubiquitination | Uniprot | |
| R37 | Methylation | Uniprot | |
| K41 | Acetylation | Uniprot | |
| K41 | Sumoylation | Uniprot | |
| K41 | Ubiquitination | Uniprot | |
| K44 | Acetylation | Uniprot | |
| K44 | Ubiquitination | Uniprot | |
| K51 | Methylation | Uniprot | |
| K51 | Ubiquitination | Uniprot | |
| S53 | Phosphorylation | P05771 (PRKCB) | Uniprot |
| K55 | Acetylation | Uniprot | |
| K55 | Methylation | Uniprot | |
| K55 | Sumoylation | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| Y56 | Phosphorylation | Uniprot | |
| K62 | Methylation | Uniprot | |
| K62 | Ubiquitination | Uniprot | |
| R69 | Methylation | Uniprot | |
| K79 | Acetylation | Uniprot | |
| K79 | Methylation | Uniprot | |
| K84 | Methylation | Uniprot | |
| Y85 | Phosphorylation | Uniprot | |
| Y86 | Phosphorylation | Uniprot | |
| T88 | Phosphorylation | Uniprot | |
| T104 | Phosphorylation | Uniprot | |
| T106 | Phosphorylation | Uniprot | |
| S128 | Phosphorylation | Uniprot | |
| K129 | Ubiquitination | Uniprot | |
| T133 | Phosphorylation | Uniprot | |
| R134 | Methylation | Uniprot | |
| Y141 | Phosphorylation | Uniprot | |
| T142 | Phosphorylation | Uniprot | |
| K146 | Acetylation | Uniprot | |
| K146 | Ubiquitination | Uniprot | |
| K154 | Ubiquitination | Uniprot | |
| S163 | Phosphorylation | Uniprot | |
| K165 | Acetylation | Uniprot | |
| K165 | Methylation | Uniprot | |
| K165 | Ubiquitination | Uniprot | |
| R166 | Methylation | Uniprot | |
| K172 | Ubiquitination | Uniprot | |
| S175 | Phosphorylation | Uniprot | |
| Y177 | Phosphorylation | Uniprot | |
| K179 | Acetylation | Uniprot | |
| S205 | Phosphorylation | P45983 (MAPK8) | Uniprot |
| K219 | Ubiquitination | Uniprot | |
| T234 | Phosphorylation | Uniprot | |
| T239 | Phosphorylation | Uniprot | |
| K244 | Ubiquitination | Uniprot | |
| Y254 | Phosphorylation | Uniprot | |
| K255 | Acetylation | Uniprot | |
| K255 | Methylation | Uniprot | |
| K255 | Ubiquitination | Uniprot | |
| T261 | Phosphorylation | Uniprot | |
| R266 | Methylation | Uniprot | |
| T269 | Phosphorylation | Uniprot | |
| T287 | Phosphorylation | Uniprot | |
| S291 | Phosphorylation | Uniprot | |
| S300 | Phosphorylation | Uniprot | |
| K313 | Sumoylation | Uniprot | |
| K313 | Ubiquitination | Uniprot | |
| K318 | Acetylation | Uniprot | |
| K318 | Methylation | Uniprot | |
| K318 | Ubiquitination | Uniprot | |
| S358 | Phosphorylation | P45983 (MAPK8) | Uniprot |
| S383 | Phosphorylation | Uniprot | |
| K392 | Ubiquitination | Uniprot | |
| S393 | Phosphorylation | Uniprot | |
| R430 | Methylation | Uniprot | |
| T432 | Phosphorylation | Uniprot | |
| K439 | Acetylation | Uniprot | |
| S445 | Phosphorylation | Uniprot | |
| T452 | Phosphorylation | Uniprot | |
| K453 | Ubiquitination | Uniprot |
研究背景
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
Trimethylated at Lys-165 by EEF1AKMT3. Mono-, di-, and trimethylated at Lys-36 by EEF1AKMT4; trimethylated form is predominant. Methylation by EEF1AKMT4 contributes to the fine-tuning of translation rates for a subset of tRNAs. Trimethylated at the N-terminus by EEF1AKNMT. Mono- and dimethylated at Lys-55 by EEF1AKNMT; dimethylated form is predominant.
Nucleus.
Brain, heart, and skeletal muscle.
Monomer.
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
研究领域
· Genetic Information Processing > Translation > RNA transport.
· Human Diseases > Infectious diseases: Bacterial > Legionellosis.
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