| 产品: | PLD2 抗体 |
| 货号: | AF6974 |
| 描述: | Rabbit polyclonal antibody to PLD2 |
| 应用: | ELISA(peptide) |
| 反应: | Human, Mouse, Rat |
| 分子量: | 106kD(Calculated). |
| 蛋白号: | O14939 |
| RRID: | AB_2847764 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF6974, RRID:AB_2847764.
展开/折叠
Choline phosphatase 2; EC 3.1.4.4; hPLD 2; hPLD2; mPLD2; Phosphatidylcholine hydrolyzing phospholipase D2; Phosphatidylcholine-hydrolyzing phospholipase D2; Phospholipase D2; PhospholipaseD2; PLD 2; PLD1C; Pld2; PLD2_HUMAN; Pldc; rPLD2;
抗原和靶标
A synthesized peptide derived from human PLD2.
- O14939 PLD2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFLAIYELQSLKVHPLVFAPGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVLMSLLPLARFAVAYSPARDAGNREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMSFYRNYHAMTEFLEVSQLSFIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVVKDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYRQARWWAQEITELAQGPGRDFLQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRALMLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGDSSESAASQPPTPRPDSPATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPWRDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLPFTLPGGQCTTVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDEIVDRILKAHKQGWCYRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKVLIADDRTVIIGSANINDRSLLGKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFGVILGANTRPDLDLRDPICDDFFQLWQDMAESNANIYEQIFRCLPSNATRSLRTLREYVAVEPLATVSPPLARSELTQVQGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT
翻译修饰 - O14939 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T29 | Phosphorylation | Uniprot | |
| T72 | Phosphorylation | Uniprot | |
| S77 | Phosphorylation | Uniprot | |
| S79 | Phosphorylation | Uniprot | |
| K80 | Ubiquitination | Uniprot | |
| T99 | Phosphorylation | Uniprot | |
| T100 | Phosphorylation | Uniprot | |
| K118 | Ubiquitination | Uniprot | |
| S134 | Phosphorylation | Q00535 (CDK5) | Uniprot |
| S146 | Phosphorylation | Uniprot | |
| T156 | Phosphorylation | Uniprot | |
| S161 | Phosphorylation | Uniprot | |
| Y169 | Phosphorylation | Uniprot | |
| T175 | Phosphorylation | Uniprot | |
| Y179 | Phosphorylation | P00533 (EGFR) | Uniprot |
| S213 | Phosphorylation | Uniprot | |
| S243 | Phosphorylation | P17252 (PRKCA) | Uniprot |
| T252 | Phosphorylation | P17252 (PRKCA) | Uniprot |
| K292 | Methylation | Uniprot | |
| Y296 | Phosphorylation | P00533 (EGFR) | Uniprot |
| K388 | Methylation | Uniprot | |
| K388 | Ubiquitination | Uniprot | |
| Y415 | Phosphorylation | P52333 (JAK3) | Uniprot |
| S416 | Phosphorylation | Uniprot | |
| T488 | Phosphorylation | Uniprot | |
| Y511 | Phosphorylation | P12931 (SRC) | Uniprot |
| T566 | Phosphorylation | Q05655 (PRKCD) | Uniprot |
| Y573 | Phosphorylation | Uniprot | |
| Y578 | Phosphorylation | Uniprot | |
| Y580 | Phosphorylation | Uniprot | |
| K656 | Ubiquitination | Uniprot |
研究背景
May have a role in signal-induced cytoskeletal regulation and/or endocytosis.
Phosphorylated by FGR.
Membrane>Peripheral membrane protein.
Ubiquitous.
Interacts with EGFR (By similarity). Interacts with PIP5K1B.
Belongs to the phospholipase D family.
研究领域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
· Environmental Information Processing > Signal transduction > Ras signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > cAMP signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Sphingolipid signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Phospholipase D signaling pathway. (View pathway)
· Human Diseases > Cancers: Overview > Choline metabolism in cancer. (View pathway)
· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.
· Metabolism > Lipid metabolism > Ether lipid metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Immune system > Fc gamma R-mediated phagocytosis. (View pathway)
· Organismal Systems > Nervous system > Glutamatergic synapse.
限制条款
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