| 产品: | CDKN2AIP 抗体 |
| 货号: | DF13910 |
| 描述: | Rabbit polyclonal antibody to CDKN2AIP |
| 应用: | ELISA(peptide) |
| 反应: | Human, Mouse, Rat |
| 分子量: | 60~70kD; 61kD(Calculated). |
| 蛋白号: | Q9NXV6 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
Calcium response factor; CARF; CARF_HUMAN; CDKN2A interacting protein; CDKN2A-interacting protein; Cdkn2aip; collaborates/cooperates with ARF (alternate reading frame) protein; Collaborator of ARF; FLJ20036;
抗原和靶标
A synthesized peptide derived from Human CDKN2AIP.
- Q9NXV6 CARF_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAQEVSEYLSQNPRVAAWVEALRCDGETDKHWRHRRDFLLRNAGDLAPAGGAASASTDEAADAESGTRNRQLQQLISFSMAWANHVFLGCRYPQKVMDKILSMAEGIKVTDAPTYTTRDELVAKVKKRGISSSNEGVEEPSKKRVIEGKNSSAVEQDHAKTSAKTERASAQQENSSTCIGSAIKSESGNSARSSGISSQNSSTSDGDRSVSSQSSSSVSSQVTTAGSGKASEAEAPDKHGSASFVSLLKSSVNSHMTQSTDSRQQSGSPKKSALEGSSASASQSSSEIEVPLLGSSGSSEVELPLLSSKPSSETASSGLTSKTSSEASVSSSVAKNSSSSGTSLLTPKSSSSTNTSLLTSKSTSQVAASLLASKSSSQTSGSLVSKSTSLASVSQLASKSSSQTSTSQLPSKSTSQSSESSVKFSCKLTNEDVKQKQPFFNRLYKTVAWKLVAVGGFSPNVNHGELLNAAIEALKATLDVFFVPLKELADLPQNKSSQESIVCELRCKSVYLGTGCGKSKENAKAVASREALKLFLKKKVVVKICKRKYRGSEIEDLVLLDEESRPVNLPPALKHPQELL
研究背景
Regulates DNA damage response in a dose-dependent manner through a number of signaling pathways involved in cell proliferation, apoptosis and senescence.
May be ubiquitinated.
Nucleus>Nucleoplasm.
Ubiquitously expressed.
Interacts with CDKN2A/p14ARF, p53/TP53 and MDM2. Interacts with CHEK2 and MAPK3. Interacts with XRN2.
Belongs to the CARF family.
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