Epo-R Antibody - #AF6211

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产品: Epo-R 抗体
货号: AF6211
描述: Rabbit polyclonal antibody to Epo-R
应用: WB IF/ICC
文献验证: WB
反应: Human, Mouse, Rat, Monkey
预测: Pig, Sheep, Dog
蛋白号: P19235
RRID: AB_2835092

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   规格 价格 库存
 50ul RMB¥ 1250 现货
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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实验方案
WB Handbook
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IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human, Mouse, Rat, Monkey
克隆:
Polyclonal
特异性:
Epo-R Antibody detects endogenous levels of total Epo-R.
RRID:
AB_2835092
引用格式: Affinity Biosciences Cat# AF6211, RRID:AB_2835092.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

EPO R; EPO-R; epor; EPOR_HUMAN; Erythropoietin receptor; Erythropoietin receptor precursor; MGC138358;

抗原和靶标

免疫原:

A synthesized peptide derived from human Epo-R, corresponding to a region within the internal amino acids.

基因/基因ID:
EPOR(2057)
描述:
Erythropoiesis is regulated through the interaction of erythropoietin (Epo) with its receptor, EpoR, a member of the cytokine superfamily of receptors. The human EpoR is a 507 amino acid transmembrane protein that forms homodimers following erythropoietin activation and is related to the interleukin 2 (IL-2) receptor β chain subunit (IL-2Rβ).

研究领域

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Jak-STAT signaling pathway.   (View pathway)

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

· Organismal Systems > Immune system > Hematopoietic cell lineage.   (View pathway)

文献引用

1). Erythropoietin-mediated IL-17 F attenuates sepsis-induced gut microbiota dysbiosis and barrier dysfunction. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023 (PubMed: 37390712) [IF=6.9]
2). The Effects of Curcumae Longae Radix, Curcuma phaeocaulis Radix and Their Processed Products on Epo/EpoR Pathway and CD62p. Frontiers in Pharmacology, 2018 (PubMed: 30038572) [IF=5.6]

Application: WB    Species: rat    Sample: hepar

FIGURE 4 | Observation for EpoR protein expression in hepar. CG, control group, MG, model group, SHG, Curcumae Longae Radix group, CHG,Stir-frying Curcumae Longae Radix with vinegar group, JHG, Stir-frying Curcumae Longae Radix with wine group, SLG, Curcuma phaeocaulis Radix group, CLG, Stir-frying Curcuma phaeocaulis Radix with vinegar group, JLG,Stir-frying Curcuma phaeocaulis Radix with wine group and PoG, positive group. Values were mean ± SD (n = 6). ∗p < 0.05 and ∗∗p < 0.01 vs. Control group #p < 0.05 and ##p < 0.01 vs. model group 1p < 0.05 and P < 0.01 Curcuma phaeocaulis Radix group versus Curcumae Longae Radix group, Stir-frying Curcuma phaeocaulis Radix with vinegar group versus Stir-frying Curcumae Longae Radix with vinegar group, Stir-frying Curcuma phaeocaulis Radix with wine group versus Stir-frying Curcumae Longae Radix with wine group.

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