产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
ASGP-R 1; ASGPR 1; ASGPR; ASGPR1; Asgr1; ASGR1_HUMAN; Asialoglycoprotein receptor 1; C type lectin domain family 4 member H1; C-type lectin domain family 4 member H1; CLEC4H1; Hepatic lectin H1; HL-1;
抗原和靶标
A synthesized peptide derived from Human Asialoglycoprotein Receptor 1.
- P07306 ASGR1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTKEYQDLQHLDNEESDHHQLRKGPPPPQPLLQRLCSGPRLLLLSLGLSLLLLVVVCVIGSQNSQLQEELRGLRETFSNFTASTEAQVKGLSTQGGNVGRKMKSLESQLEKQQKDLSEDHSSLLLHVKQFVSDLRSLSCQMAALQGNGSERTCCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQHHIGPVNTWMGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGGEDCAHFTDDGRWNDDVCQRPYRWVCETELDKASQEPPLL
研究背景
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Phosphorylated on a cytoplasmic Ser residue.
Membrane>Single-pass type II membrane protein.
Secreted.
Expressed exclusively in hepatic parenchymal cells.
Interacts with LASS2.
(Microbial infection) Interacts with hepatitis E virus capsid protein ORF2.
研究领域
· Organismal Systems > Endocrine system > Thyroid hormone synthesis.
限制条款
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