产品: | ACOT7 抗体 |
货号: | DF14107 |
描述: | Rabbit polyclonal antibody to ACOT7 |
应用: | ELISA(peptide) |
反应: | Human, Mouse, Rat |
分子量: | 40kD; 42kD(Calculated). |
蛋白号: | O00154 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
ACH1; ACOT 7; ACOT7; ACT; Acyl CoA thioesterase 7; Acyl CoA thioesterase long chain; Acyl-CoA thioesterase 7; BACH; BACH_HUMAN; Brain acyl CoA hydrolase; Brain acyl-CoA hydrolase; CTE-II; CTE-IIa; Cytosolic acyl coenzyme A thioester hydrolase; hBACH; LACH; LACH1; Long chain acyl-CoA thioester hydrolase;
抗原和靶标
A synthesized peptide derived from Human ACOT7.
- O00154 BACH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKLLARALRLCEFGRQASSRRLVAGQGCVGPRRGCCAPVQVVGPRADLPPCGACITGRIMRPDDANVAGNVHGGTILKMIEEAGAIISTRHCNSQNGERCVAALARVERTDFLSPMCIGEVAHVSAEITYTSKHSVEVQVNVMSENILTGAKKLTNKATLWYVPLSLKNVDKVLEVPPVVYSRQEQEEEGRKRYEAQKLERMETKWRNGDIVQPVLNPEPNTVSYSQSSLIHLVGPSDCTLHGFVHGGVTMKLMDEVAGIVAARHCKTNIVTASVDAINFHDKIRKGCVITISGRMTFTSNKSMEIEVLVDADPVVDSSQKRYRAASAFFTYVSLSQEGRSLPVPQLVPETEDEKKRFEEGKGRYLQMKAKRQGHAEPQP
研究背景
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Acyl-coenzyme A thioesterase 7/ACOT7 preferentially hydrolyzes palmitoyl-CoA, but has a broad specificity acting on other fatty acyl-CoAs with chain-lengths of C8-C18. May play an important physiological function in brain.
Cytoplasm>Cytosol.
Cytoplasm>Cytosol.
Mitochondrion.
Mitochondrion.
Isoform 4 is expressed exclusively in brain.
Homohexamer.
Both HotDog ACOT-type hydrolase domains are required for efficient activity.
研究领域
· Metabolism > Lipid metabolism > Fatty acid elongation.
· Metabolism > Lipid metabolism > Biosynthesis of unsaturated fatty acids.
限制条款
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