产品: SDF4 抗体
货号: DF14122
描述: Rabbit polyclonal antibody to SDF4
应用: IHC IF/ICC
反应: Human, Mouse, Rat
分子量: 30~40kD; 42kD(Calculated).
蛋白号: Q9BRK5

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
克隆:
Polyclonal
特异性:
SDF4 Antibody detects endogenous levels of total SDF4.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

45 kDa calcium-binding protein; Cab45; CAB45_HUMAN; Calcium binding protein; PSEC0034; SDF 4; SDF-4; SDF4; Stromal cell derived factor 4; Stromal cell-derived factor 4;

抗原和靶标

免疫原:

A synthesized peptide derived from Human SDF4.

Uniprot:
基因/基因ID:
表达:
Q9BRK5 CAB45_HUMAN:

Ubiquitous. Isoform 5 is expressed in pancreas.

序列:
MVWPWVAMASRWGPLIGLAPCCLWLLGAVLLMDASARPANHSSTRERVANREENEILPPDHLNGVKLEMDGHLNRGFHQEVFLGKDLGGFDEDAEPRRSRRKLMVIFSKVDVNTDRKISAKEMQRWIMEKTAEHFQEAMEESKTHFRAVDPDGDGHVSWDEYKVKFLASKGHSEKEVADAIRLNEELKVDEETQEVLENLKDRWYQADSPPADLLLTEEEFLSFLHPEHSRGMLRFMVKEIVRDLDQDGDKQLSVPEFISLPVGTVENQQGQDIDDNWVKDRKKEFEELIDSNHDGIVTAEELESYMDPMNEYNALNEAKQMIAVADENQNHHLEPEEVLKYSEFFTGSKLVDYARSVHEEF

研究背景

功能:

May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.

Isoform 5 may be involved in the exocytosis of zymogens by pancreatic acini.

细胞定位:

Golgi apparatus lumen.

Cytoplasm. Cell membrane. Cell projection>Bleb.
Note: Isoform 5 colocalizes with STX3 and STXBP1 isoform 2 at the plasma membrane and cell surface blebs.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Ubiquitous. Isoform 5 is expressed in pancreas.

亚基结构:

Isoform 5 interacts with STXBP1; the interaction is enhanced in presence of calcium. Isoform 5 interacts with STX3.

蛋白家族:

Binds calcium via its EF-hands (By similarity). Isoform 5 binds calcium.

Belongs to the CREC family.

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