产品: BDH2 抗体
货号: DF14214
描述: Rabbit polyclonal antibody to BDH2
应用: IHC IF/ICC
反应: Human, Mouse, Rat
分子量: 27kD; 27kD(Calculated).
蛋白号: Q9BUT1

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

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产品描述

来源:
Rabbit
应用:
IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human,Mouse,Rat
克隆:
Polyclonal
特异性:
BDH2 Antibody detects endogenous levels of total BDH2.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

3 hydroxybutyrate dehydrogenase type 2; 3-hydroxybutyrate dehydrogenase type 2; BDH 2; BDH2; BDH2_HUMAN; Dehydrogenase/reductase (SDR family) member 6; Dehydrogenase/reductase SDR family member 6; DHRS6; EFA6R; FLJ13261; Oxidoreductase ucpA; PRO20933; R beta hydroxybutyrate dehydrogenase; R-beta-hydroxybutyrate dehydrogenase; SDR15C1; Short chain dehydrogenase/reductase family 15C member 1; UCPA OR; UNQ6308;

抗原和靶标

免疫原:

A synthesized peptide derived from Human BDH2.

Uniprot:
基因/基因ID:
表达:
Q9BUT1 BDH2_HUMAN:

Detected in liver (at protein level).

序列:
MGRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNPVIIDGGWSL

研究背景

功能:

Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron assimilation and homeostasis. Plays a role in susceptibility to bacterial infection by providing an assimilable source of iron that is exploited by pathogenic bacteria (By similarity). Also acts as a 3-hydroxybutyrate dehydrogenase.

细胞定位:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Detected in liver (at protein level).

亚基结构:

Homotetramer.

蛋白家族:

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

研究领域

· Metabolism > Lipid metabolism > Synthesis and degradation of ketone bodies.

· Metabolism > Carbohydrate metabolism > Butanoate metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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