产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
38 kDa DNA polymerase delta interaction protein; delta interacting protein 2; DNA polymerase delta interaction protein p38; p38; PDIP 2; PDIP 38; PDIP2; PDIP2_HUMAN; PDIP38; POLD 4; POLD4; Poldip2; Polymerase (DNA directed) delta interacting protein 2; Polymerase delta interacting protein 38; Polymerase delta-interacting protein 2;
抗原和靶标
A synthesized peptide derived from human POLDIP2.
- Q9Y2S7 PDIP2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAACTARRALAVGSRWWSRSLTGARWPRPLCAAAGAGAFSPASTTTTRRHLSSRNRPEGKVLETVGVFEVPKQNGKYETGQLFLHSIFGYRGVVLFPWQARLYDRDVASAAPEKAENPAGHGSKEVKGKTHTYYQVLIDARDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHEDILPYTSTDQVPIQHELFERFLLYDQTKAPPFVARETLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSDVVQLRERHWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVRIPPFSLESNKDEKTPPSGLHW
研究背景
Involved in DNA damage tolerance by regulating translesion synthesis (TLS) of templates carrying DNA damage lesions such as 8oxoG and abasic sites. May act by stimulating activity of DNA polymerases involved in TLS, such as PRIMPOL and polymerase delta (POLD1).
Mitochondrion matrix. Nucleus.
Note: Mainly localizes to the mitochondrial matrix; a small fraction localizes in the nucleus.
Interacts with PCNA and POLD2. Interacts with SSBP1. Interacts with PRIMPOL; leading to enhance DNA polymerase activity of PRIMPOL. Interacts with POLH. Interacts with POLD1; leading to stimulate DNA polymerase activity of POLD1.
限制条款
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