产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
3-keto acyl-CoA synthase Elovl3; CIG30; Cold-inducible glycoprotein of 30 kDa; Elongation of very long chain fatty acids protein 3; ELOV3_HUMAN; Elovl3; MGC21435;
抗原和靶标
A synthesized peptide derived from human ELOVL3.
- Q9HB03 ELOV3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVTAMNVSHEVNQLFQPYNFELSKDMRPFFEEYWATSFPIALIYLVLIAVGQNYMKERKGFNLQGPLILWSFCLAIFSILGAVRMWGIMGTVLLTGGLKQTVCFINFIDNSTVKFWSWVFLLSKVIELGDTAFIILRKRPLIFIHWYHHSTVLVYTSFGYKNKVPAGGWFVTMNFGVHAIMYTYYTLKAANVKPPKMLPMLITSLQILQMFVGAIVSILTYIWRQDQGCHTTMEHLFWSFILYMTYFILFAHFFCQTYIRPKVKAKTKSQ
研究背景
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and unsaturated acyl-CoA substrates with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
N-Glycosylated.
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Testis.
The C-terminal di-lysine motif may confer endoplasmic reticulum localization.
Belongs to the ELO family. ELOVL3 subfamily.
研究领域
· Metabolism > Lipid metabolism > Fatty acid elongation.
限制条款
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