产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
60S ribosomal protein L23A; FLJ27455; L23A; MDA20; Melanoma differentiation-associated gene 20; Ribosomal protein L23a; RL23A_HUMAN; RPL23A;
抗原和靶标
A synthesized peptide derived from human RPL23A.
- P62750 RL23A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAPKAKKEAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII
研究背景
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination.
N-terminus is methylated by METTL11A/NTM1.
Citrullinated by PADI4.
Interacts with LYAR and GNL2. Interacts with MDM2; this interaction may promote MDM2-mediated p53/TP53 polyubiquitination.
Belongs to the universal ribosomal protein uL23 family.
研究领域
· Genetic Information Processing > Translation > Ribosome.
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