产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
ATP 6G; ATP 6J; ATP6G; ATP6G1; ATP6GL; ATP6V1G1; ATPase H+ transporting lysosomal (vacuolar proton pump) member J; ATPase H+ transporting lysosomal 13kD V1 subunit G isoform 1; ATPase H+ transporting lysosomal 13kDa V1 subunit G1; ATPase H+ transporting lysosomal member J; ATPase H+ transporting lysosomal subunit G isoform 1; DKFZp547P234; V ATPase 13 kDa subunit 1; V ATPase G subunit 1; Vacuolar ATP synthase subunit G 1; Vacuolar ATP synthase subunit G1; Vacuolar ATP synthase subunit M16; Vacuolar H+ ATPase G1; Vacuolar H+ ATPase subunit G 1; Vacuolar proton pump G subunit 1; Vma 10; Vma10;
抗原和靶标
A synthesized peptide derived from human ATP6V1G1.
- O75348 VATG1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASQSQGIQQLLQAEKRAAEKVSEARKRKNRRLKQAKEEAQAEIEQYRLQREKEFKAKEAAALGSRGSCSTEVEKETQEKMTILQTYFRQNRDEVLDNLLAFVCDIRPEIHENYRING
研究背景
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation.
Ubiquitous.
V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d).
Belongs to the V-ATPase G subunit family.
研究领域
· Cellular Processes > Transport and catabolism > Phagosome. (View pathway)
· Environmental Information Processing > Signal transduction > mTOR signaling pathway. (View pathway)
· Human Diseases > Infectious diseases: Bacterial > Vibrio cholerae infection.
· Human Diseases > Infectious diseases: Bacterial > Epithelial cell signaling in Helicobacter pylori infection.
· Human Diseases > Immune diseases > Rheumatoid arthritis.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Synaptic vesicle cycle.
· Organismal Systems > Excretory system > Collecting duct acid secretion.
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