产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
2310015C21Rik,; Integrin beta 1 binding protein 3; Integrin beta-1-binding protein 3; Itgb1bp3; MGC126624; MIBP; Muscle integrin binding protein; Muscle integrin-binding protein; Muscle specific beta 1 integrin binding protein; Nicotinamide riboside kinase 2; Nicotinic acid riboside kinase 2; NmR K 2; NmR-K 2; NRK 2; NRK2; NRK2_HUMAN; Ribosylnicotinamide kinase 2; Ribosylnicotinic acid kinase 2; RNK 2;
抗原和靶标
A synthesized peptide derived from human NMRK2.
Predominantly expressed in skeletal muscle and, at a much lower level, in the heart (at protein level). No expression in brain, kidney, liver, lung, pancreas nor placenta.
- Q9NPI5 NRK2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKLIVGIGGMTNGGKTTLTNSLLRALPNCCVIHQDDFFKPQDQIAVGEDGFKQWDVLESLDMEAMLDTVQAWLSSPQKFARAHGVSVQPEASDTHILLLEGFLLYSYKPLVDLYSRRYFLTVPYEECKWRRSTRNYTVPDPPGLFDGHVWPMYQKYRQEMEANGVEVVYLDGMKSREELFREVLEDIQNSLLNRSQESAPSPARPARTQGPGRGCGHRTARPAASQQDSM
研究背景
Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis.
Predominantly expressed in skeletal muscle and, at a much lower level, in the heart (at protein level). No expression in brain, kidney, liver, lung, pancreas nor placenta.
Monomer (By similarity). Interacts with ITGB1 alone or when associated with alpha-7, but not with alpha-5.
Belongs to the uridine kinase family. NRK subfamily.
研究领域
· Metabolism > Metabolism of cofactors and vitamins > Nicotinate and nicotinamide metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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