UROS Antibody - #DF16065

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产品: UROS 抗体
货号: DF16065
描述: Rabbit polyclonal antibody to UROS
应用: IF/ICC
反应: Human
分子量: 29kD(Calculated).
蛋白号: P10746

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   规格 价格 库存
 100ul RMB¥ 2300 现货
 200ul RMB¥ 3000 现货

货期: 当天发货

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MS Report
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实验方案
WB Handbook
IHC Protocol
IF/ICC Protocol

产品描述

来源:
Rabbit
应用:
IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
克隆:
Polyclonal
特异性:
UROS Antibody detects endogenous levels of UROS.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

congenital erythropoietic porphyria; HEM4_HUMAN; Hydroxymethylbilane hydrolyase [cyclizing]; Hydroxymethylbilane hydrolyase; OTTHUMP00000020709; OTTHUMP00000020710; UROIIIS; Uroporphyrinogen III cosynthetase; Uroporphyrinogen III synthase (congenital erythropoietic porphyria); Uroporphyrinogen III synthase; Uroporphyrinogen-III cosynthase; Uroporphyrinogen-III synthase; UROS;

抗原和靶标

免疫原:

A synthesized peptide derived from human UROS.

Uniprot:

P10746(HEM4_HUMAN) >>Visit HPA database.

基因/基因ID:
UROS(7390)
表达:
P10746 HEM4_HUMAN:

Ubiquitous.

序列:
MKVLLLKDAKEDDCGQDPYIRELGLYGLEATLIPVLSFEFLSLPSFSEKLSHPEDYGGLIFTSPRAVEAAELCLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCGNAEKLAEYICSRESSALPLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNLNSYYSQQGVPASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVSCTAESPTPQALATGIRKALQPHGCC

研究背景

功能:

Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of porphyrins. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as methionine synthesis (vitamin B12) or oxygen transport (heme).

组织特异性:

Ubiquitous.

亚基结构:

Monomer.

蛋白家族:

Belongs to the uroporphyrinogen-III synthase family.

研究领域

· Metabolism > Metabolism of cofactors and vitamins > Porphyrin and chlorophyll metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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