产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
CD158 antigen like family member K; CD158 antigen-like family member K; CD158k; KI3L2_HUMAN; Killer cell immunoglobulin like receptor 3DL2; killer cell immunoglobulin like receptor KIR3DL2; Killer cell immunoglobulin like receptor, three domains, long cytoplasmic tail, 2; Killer cell immunoglobulin-like receptor 3DL2; KIR antigen 3DL2; KIR3DL2; Kirl2; MHC class I NK cell receptor; Natural killer associated transcript 4; natural killer cell inhibitory receptor; Natural killer-associated transcript 4; NK associated transcript 4; NK associated transcript 4A, included; NK associated transcript 4B, included; NKAT-4; NKAT4; NKAT4B; p140; p70 natural killer cell receptor clone CL 5; p70 natural killer cell receptor clone CL-5; p70 NK receptor CL 5; p70 NK receptor CL-5;
抗原和靶标
A synthesized peptide derived from human KIR3DL2.
- P43630 KI3L2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLLYRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKTPLTDTSVYTELPNAEPRSKVVSCPRAPQSGLEGVF
研究背景
Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity.
Cell membrane>Single-pass type I membrane protein.
Expressed in astrocytes.
Interacts with peptide-free HLA-F open conformer.
Belongs to the immunoglobulin superfamily.
研究领域
· Human Diseases > Immune diseases > Graft-versus-host disease.
· Organismal Systems > Immune system > Antigen processing and presentation. (View pathway)
· Organismal Systems > Immune system > Natural killer cell mediated cytotoxicity. (View pathway)
限制条款
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