产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
展开/折叠
EPB72 like 1; hUNC 24; SLP 1; SLP1; Stomatin (EBP72) like 1; Stomatin related protein; STORP; UNC24;
抗原和靶标
A synthesized peptide derived from human STOML1.
- Q9UBI4 STML1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLGRSGYRALPLGDFDRFQQSSFGFLGSQKGCLSPERGGVGTGADVPQSWPSCLCHGLISFLGFLLLLVTFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLRTRAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLKRPLREIQMEKLKISDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQDSPAGPNLDSTLQQLALHFLGGSMNSMAGGAPSPGPADTVEMVSEVEPPAPQVGARSSPKQPLAEGLLTALQPFLSEALVSQVGACYQFNVVLPSGTQSAYFLDLTTGRGRVGHGVPDGIPDVVVEMAEADLRALLCRELRPLGAYMSGRLKVKGDLAMAMKLEAVLRALK
研究背景
May play a role in cholesterol transfer to late endosomes. May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of ASIC3. May be involved in regulation of proton sensing in dorsal root ganglions (By similarity). May play a role in protecting FBXW7 isoform 3 from degradation.
Membrane>Single-pass type III membrane protein. Late endosome membrane. Membrane raft. Cell membrane>Single-pass type III membrane protein. Cytoplasmic vesicle.
Ubiquitously expressed at low levels. Expression is highest in brain.
Interacts with STOM; may redistribute STOM from the plasma membrane to late endosomes. Interacts with FBXW7 isoform 3 and CDK2.
Belongs to the band 7/mec-2 family.
限制条款
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