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产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# AF0308, RRID:AB_2833472.
展开/折叠
4933422O14Rik; 9630002F18; AI845682; AI848168; BB075781; D17Bwg0511e; DAP 1 ALPHA; DAP 1; DAP 1 BETA; DAP-1; DAP-1-ALPHA; DAP-1-BETA; DAP1; Discs large (Drosophila) homolog associated protein 1; Discs large homolog associated protein 1; Disks large associated protein 1; Disks large associated protein 1, alpha isoform, included; Disks large associated protein 1, beta isoform, included; Disks large-associated protein 1; DLGAP 1; Dlgap1; DLGP1_HUMAN; GKAP; GKAP/SAPAP; GKPA/SAPAP; Guanylate kinase associated protein; Guanylate kinase-associated protein; hGKAP; KIAA4162; MGC88156; mKIAA4162; PSD 95/SAP90 binding protein 1; PSD-95/SAP90-binding protein 1; SAP90/PSD 95 associated protein 1; SAP90/PSD-95-associated protein 1; SAPAP 1; SAPAP1;
抗原和靶标
- O14490 DLGP1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKGLSGSRSHHHGVTCDSACDSLSHHSDRKPYLLSPVEHHPADHPYYTQRNSFQAECVGPFSDPLASSTFPRRHYTSQQELKDECALVPRTLATKANRIPANLLDQFERQLPLSRDGYHTLQYKRTAVEHRSDSPGRIRHLVHSVQKLFTKSHSLEGPSKGSVNGGKASPDEAQAARYGKRSKSKERRAEPKARPSTSPGWWSSDDNLDGDMCIYHAPSGVMTMGRCPDRSASQYFLEAYNTISEQAVKASRSNNDVKCSTCANLPVSLDTPLLKKSAWSSTLTVSRAREVYQKASVNMDQAMVKSESCQQERSCQYLQVPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMGDEDSGDSDTSPKPSPKVAARRESYLKATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRNESYMRAMSTISQVSEMEVNGQFESVCESVFSELESQAVEALDLPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDIISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNTATVTTTTTIATVTTEDRKKDHFKKNRCLSIGIQVDDAEEPDKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKERRAPPPVPKKPAKGPAPLIRERSLESSQRQEARKRLMAAKRAASVRQNSATESAESIEIYIPEAQTRL
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O14490 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S7 | Phosphorylation | Uniprot | |
| S24 | Phosphorylation | Uniprot | |
| S52 | Phosphorylation | Uniprot | |
| Y118 | Phosphorylation | Uniprot | |
| S154 | Phosphorylation | Uniprot | |
| S169 | Phosphorylation | Uniprot | |
| S314 | Phosphorylation | Uniprot | |
| Y317 | Phosphorylation | Uniprot | |
| S346 | Phosphorylation | Uniprot | |
| S356 | Phosphorylation | Uniprot | |
| S359 | Phosphorylation | Uniprot | |
| S375 | Phosphorylation | Uniprot | |
| S383 | Phosphorylation | Uniprot | |
| S397 | Phosphorylation | Uniprot | |
| S406 | Phosphorylation | Uniprot | |
| S412 | Phosphorylation | Uniprot | |
| S415 | Phosphorylation | Uniprot | |
| S419 | Phosphorylation | Uniprot | |
| S422 | Phosphorylation | Uniprot | |
| S440 | Phosphorylation | Uniprot | |
| S491 | Phosphorylation | Uniprot | |
| S493 | Phosphorylation | Uniprot | |
| K500 | Ubiquitination | Uniprot | |
| S503 | Phosphorylation | Uniprot | |
| S510 | Phosphorylation | Uniprot | |
| T530 | Phosphorylation | Uniprot | |
| T536 | Phosphorylation | Uniprot | |
| T537 | Phosphorylation | Uniprot | |
| T541 | Phosphorylation | Uniprot | |
| S589 | Phosphorylation | Uniprot | |
| S592 | Phosphorylation | Uniprot | |
| S595 | Phosphorylation | Uniprot | |
| S651 | Phosphorylation | Uniprot | |
| K673 | Acetylation | Uniprot | |
| S958 | Phosphorylation | Uniprot |
研究背景
Part of the postsynaptic scaffold in neuronal cells.
Cell membrane>Peripheral membrane protein. Cell junction>Synapse>Postsynaptic density. Cell junction>Synapse.
Expressed in brain.
Interacts with guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1 (By similarity). Interacts with MPP2 (via the SH3-Guanylate kinase-like sub-module) (By similarity).
Belongs to the SAPAP family.
研究领域
· Organismal Systems > Nervous system > Glutamatergic synapse.
文献引用
Application: IF/ICC Species: mouse Sample: heart
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