| 产品: | PFKFB1 抗体 |
| 货号: | DF3098 |
| 描述: | Rabbit polyclonal antibody to PFKFB1 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Zebrafish, Bovine, Horse, Sheep, Rabbit, Xenopus |
| 分子量: | 58 KD; 55kD(Calculated). |
| 蛋白号: | P16118 |
| RRID: | AB_2835398 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3098, RRID:AB_2835398.
展开/折叠
6 phosphofructo 2 kinase/ fructose 2,6 bisphosphatase; 6 phosphofructo 2 kinase/fructose 2,6 biphosphatase 3; 6-bisphosphatase; 6-P2ase 3; 6-P2ASE brain/placenta-type isozyme; 6PF 2 K/Fru 2,6 P2ASE brain/placenta type isozyme; 6PF 2-K/Fru 2,6 P2ase 3; 6PF-2-K/Fru-2; F263_HUMAN; fructose 6 phosphate,2 kinase/fructose 2, 6 bisphosphatase; Fructose-2; Inducible 6 phosphofructo 2 kinase/fructose 2,6 bisphosphatase; iPFK 2; iPFK-2; IPFK2; PFK/FBPase 3; PFK2; PFKFB3; Renal carcinoma antigen NY REN 56; Renal carcinoma antigen NY-REN-56; uPFK 2;
抗原和靶标
- P16118 F261_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P16118 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| S24 | Phosphorylation | Uniprot | |
| T39 | Phosphorylation | Uniprot | |
| T133 | Phosphorylation | Uniprot | |
| Y200 | Phosphorylation | Uniprot | |
| Y204 | Phosphorylation | Uniprot | |
| Y227 | Phosphorylation | Uniprot | |
| Y242 | Phosphorylation | Uniprot | |
| Y243 | Phosphorylation | Uniprot | |
| S262 | Phosphorylation | Uniprot | |
| K364 | Ubiquitination | Uniprot | |
| Y438 | Phosphorylation | Uniprot |
研究背景
Synthesis and degradation of fructose 2,6-bisphosphate.
Liver.
Homodimer.
In the C-terminal section; belongs to the phosphoglycerate mutase family.
研究领域
· Environmental Information Processing > Signal transduction > AMPK signaling pathway. (View pathway)
· Metabolism > Carbohydrate metabolism > Fructose and mannose metabolism.
· Organismal Systems > Endocrine system > Glucagon signaling pathway.
限制条款
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