| 产品: | ZNF265 抗体 |
| 货号: | DF3054 |
| 描述: | Rabbit polyclonal antibody to ZNF265 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 34 KD; 37kD(Calculated). |
| 蛋白号: | O95218 |
| RRID: | AB_2835437 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3054, RRID:AB_2835437.
展开/折叠
ZRANB 2; DKFZp686J1831; DKFZp686N09117; FLJ41119; OTTHUMP00000011240; OTTHUMP00000011241; Zinc finger protein 265; Zinc finger RAN binding domain containing 2; Zinc finger Ran binding domain containing protein 2; Zinc finger splicing; ZIS; ZIS1; ZIS2; ZNF265;
抗原和靶标
- O95218 ZRAB2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKMMKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O95218 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S9 | Phosphorylation | Uniprot | |
| T50 | Phosphorylation | Uniprot | |
| K54 | Acetylation | Uniprot | |
| K54 | Ubiquitination | Uniprot | |
| K59 | Acetylation | Uniprot | |
| K59 | Ubiquitination | Uniprot | |
| R61 | Methylation | Uniprot | |
| S65 | Phosphorylation | Uniprot | |
| S83 | Phosphorylation | Uniprot | |
| T90 | Phosphorylation | Uniprot | |
| K92 | Acetylation | Uniprot | |
| Y93 | Phosphorylation | Uniprot | |
| K95 | Sumoylation | Uniprot | |
| K95 | Ubiquitination | Uniprot | |
| Y102 | Phosphorylation | Uniprot | |
| Y114 | Phosphorylation | Uniprot | |
| S120 | Phosphorylation | Uniprot | |
| Y124 | Phosphorylation | Uniprot | |
| K137 | Methylation | Uniprot | |
| S143 | Phosphorylation | Uniprot | |
| S153 | Phosphorylation | Uniprot | |
| S165 | Phosphorylation | Uniprot | |
| K168 | Ubiquitination | Uniprot | |
| S181 | Phosphorylation | Uniprot | |
| K182 | Ubiquitination | Uniprot | |
| Y183 | Phosphorylation | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| S193 | Phosphorylation | Uniprot | |
| S206 | Phosphorylation | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| S213 | Phosphorylation | Uniprot | |
| S217 | Phosphorylation | Uniprot | |
| S218 | Phosphorylation | Uniprot | |
| S221 | Phosphorylation | Uniprot | |
| S249 | Phosphorylation | Uniprot | |
| S273 | Phosphorylation | Uniprot | |
| S275 | Phosphorylation | Uniprot | |
| S279 | Phosphorylation | Uniprot | |
| S280 | Phosphorylation | Uniprot | |
| S288 | Phosphorylation | Uniprot | |
| S290 | Phosphorylation | Uniprot | |
| T303 | Phosphorylation | Uniprot | |
| S305 | Phosphorylation | Uniprot | |
| S307 | Phosphorylation | Uniprot | |
| S318 | Phosphorylation | Uniprot | |
| S323 | Phosphorylation | Uniprot | |
| S326 | Phosphorylation | Uniprot |
研究背景
Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.
Isoform 2 is phosphorylated on Ser-310 upon DNA damage, probably by ATM or ATR.
Nucleus.
Interacts with the C-terminal half of SNRNP70, the Arg/Ser-rich domain of AKAP17A as well as with U2AF1 and CLK1.
The RanBP2-type zinc fingers mediate binding to RNA.
Belongs to the ZRANB2 family.
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