| 产品: | SIX6 抗体 |
| 货号: | DF3059 |
| 描述: | Rabbit polyclonal antibody to SIX6 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 28 KD; 28kD(Calculated). |
| 蛋白号: | O95475 |
| RRID: | AB_2835442 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3059, RRID:AB_2835442.
展开/折叠
Homeobox protein SIX6; Homeodomain protein OPTX2; MCOPCT 2; MCOPCT2; Optic homeobox 2; OPTX 2; OPTX2; Sine oculis homeobox homolog 6; SIX 6; Six 9; SIX homeobox 6; Six6; SIX6_HUMAN; Six9;
抗原和靶标
Expressed in the developing and adult retina. Also expressed in the hypothalamic and the pituitary regions.
- O95475 SIX6_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFQLPILNFSPQQVAGVCETLEESGDVERLGRFLWSLPVAPAACEALNKNESVLRARAIVAFHGGNYRELYHILENHKFTKESHAKLQALWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFKERTRHLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQQQVLSQGSGRALRAEGDGTPEVLGVATSPAASLSSKAATSAISITSSDSECDI
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - O95475 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S10 | Phosphorylation | Uniprot | |
| K49 | Ubiquitination | Uniprot | |
| Y96 | Phosphorylation | Uniprot | |
| K112 | Ubiquitination | Uniprot | |
| K131 | Ubiquitination | Uniprot | |
| K136 | Ubiquitination | Uniprot | |
| Y147 | Phosphorylation | Uniprot | |
| Y152 | Phosphorylation | Uniprot | |
| S156 | Phosphorylation | Uniprot | |
| S198 | Phosphorylation | Uniprot | |
| S201 | Phosphorylation | Uniprot | |
| T212 | Phosphorylation | Uniprot | |
| T220 | Phosphorylation | Uniprot | |
| S221 | Phosphorylation | Uniprot | |
| S225 | Phosphorylation | Uniprot | |
| S227 | Phosphorylation | Uniprot | |
| S228 | Phosphorylation | Uniprot |
研究背景
May be involved in eye development.
Nucleus.
Expressed in the developing and adult retina. Also expressed in the hypothalamic and the pituitary regions.
Interacts with TLE4 and TLE5.
Belongs to the SIX/Sine oculis homeobox family.
限制条款
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