| 产品: | CKMT2 抗体 |
| 货号: | DF3104 |
| 描述: | Rabbit polyclonal antibody to CKMT2 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 48 KD; 48kD(Calculated). |
| 蛋白号: | P17540 |
| RRID: | AB_2835481 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3104, RRID:AB_2835481.
展开/折叠
CKMT 2; Basic-type mitochondrial creatine kinase; CKMT2; CPK; Creatine kinase mitochondrial 2; Creatine kinase mitochondrial 2 (sarcomeric); Creatine kinase S-type; creatine kinase S-type, mitochondrial; Creatine kinase, sarcomeric mitochondrial; KCRS_HUMAN; Mib CK; Mib-CK; mitochondrial; OTTHUMP00000147542; S-MtCK; Sarcomeric mitochondrial creatine kinase; SMTCK;
抗原和靶标
- P17540 KCRS_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASIFSKLLTGRNASLLFATMGTSVLTTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGKK
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P17540 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y73 | Phosphorylation | Uniprot | |
| Y85 | Phosphorylation | Uniprot | |
| T142 | Phosphorylation | Uniprot | |
| T143 | Phosphorylation | Uniprot | |
| S148 | Phosphorylation | Uniprot | |
| T151 | Phosphorylation | Uniprot | |
| Y159 | Phosphorylation | Uniprot | |
| S162 | Phosphorylation | Uniprot | |
| S163 | Phosphorylation | Uniprot | |
| T167 | Phosphorylation | Uniprot | |
| S170 | Phosphorylation | Uniprot | |
| S175 | Phosphorylation | Uniprot | |
| Y207 | Phosphorylation | Uniprot | |
| Y208 | Phosphorylation | Uniprot | |
| S211 | Phosphorylation | Uniprot | |
| T214 | Phosphorylation | Uniprot | |
| Y255 | Phosphorylation | Uniprot | |
| K281 | Acetylation | Uniprot | |
| Y313 | Phosphorylation | Uniprot | |
| S319 | Phosphorylation | Uniprot | |
| S343 | Phosphorylation | Uniprot | |
| R350 | Methylation | Uniprot | |
| T356 | Phosphorylation | Uniprot | |
| T361 | Phosphorylation | Uniprot | |
| Y368 | Phosphorylation | Uniprot | |
| S371 | Phosphorylation | Uniprot | |
| Y393 | Phosphorylation | Uniprot | |
| K419 | Acetylation | Uniprot |
研究背景
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Mitochondrion inner membrane>Peripheral membrane protein>Intermembrane side.
Sarcomere-specific. Found only in heart and skeletal muscles.
Exists as an octamer composed of four CKMT2 homodimers.
Belongs to the ATP:guanido phosphotransferase family.
研究领域
· Metabolism > Amino acid metabolism > Arginine and proline metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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