| 产品: | ERCC5 抗体 |
| 货号: | DF3143 |
| 描述: | Rabbit polyclonal antibody to ERCC5 |
| 应用: | WB IF/ICC |
| 反应: | Human |
| 预测: | Bovine, Dog |
| 分子量: | 130 KD; 133kD(Calculated). |
| 蛋白号: | P28715 |
| RRID: | AB_2835520 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3143, RRID:AB_2835520.
展开/折叠
COFS 3; COFS3; DNA excision repair protein ERCC 5; DNA excision repair protein ERCC-5; DNA excision repair protein ERCC5; DNA repair protein complementing XP G cells; DNA repair protein complementing XP-G cells; DNA repair protein complementing XPG cells; ERCC 5; ERCC5; ERCC5_HUMAN; ERCM 2; ERCM2; Excision repair cross complementation group 5; Excision Repair Cross Complementing Rodent Repair Deficiency; Excision repair cross complementing rodent repair deficiency complementation group 5; Excision repair protein; OTTHUMP00000064902; UVDR; Xeroderma Pigmentosum Complementation Group G; Xeroderma pigmentosum complementation group G protein; Xeroderma pigmentosum group G complementing protein; Xeroderma pigmentosum group G-complementing protein; XPG; XPG complementing protein; XPGC;
抗原和靶标
- P28715 ERCC5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVTCMLRKEKEAAASEIEAVSVAMEKEFELLDKAKGKTQKRGITNTLEESSSLKRKRLSDSKGKNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKEKMVLVTARSVFGKKRRKLRRARGRKRKT
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P28715 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K8 | Acetylation | Uniprot | |
| K8 | Ubiquitination | Uniprot | |
| K64 | Ubiquitination | Uniprot | |
| S100 | Phosphorylation | Uniprot | |
| K111 | Ubiquitination | Uniprot | |
| K120 | Ubiquitination | Uniprot | |
| K126 | Ubiquitination | Uniprot | |
| S156 | Phosphorylation | Uniprot | |
| S157 | Phosphorylation | Uniprot | |
| K172 | Ubiquitination | Uniprot | |
| K209 | Ubiquitination | Uniprot | |
| T217 | Phosphorylation | Uniprot | |
| K235 | Ubiquitination | Uniprot | |
| K240 | Ubiquitination | Uniprot | |
| K252 | Ubiquitination | Uniprot | |
| K274 | Ubiquitination | Uniprot | |
| Y289 | Phosphorylation | Uniprot | |
| K293 | Ubiquitination | Uniprot | |
| K298 | Ubiquitination | Uniprot | |
| S307 | Phosphorylation | Uniprot | |
| K313 | Ubiquitination | Uniprot | |
| S318 | Phosphorylation | Uniprot | |
| K322 | Ubiquitination | Uniprot | |
| T331 | Phosphorylation | Uniprot | |
| T338 | Phosphorylation | Uniprot | |
| S341 | Phosphorylation | Uniprot | |
| T344 | Phosphorylation | Uniprot | |
| S355 | Phosphorylation | Uniprot | |
| S356 | Phosphorylation | Uniprot | |
| S357 | Phosphorylation | Uniprot | |
| S363 | Phosphorylation | Uniprot | |
| S382 | Phosphorylation | Uniprot | |
| S384 | Phosphorylation | Uniprot | |
| S389 | Phosphorylation | Uniprot | |
| K392 | Ubiquitination | Uniprot | |
| K402 | Ubiquitination | Uniprot | |
| S423 | Phosphorylation | Uniprot | |
| S424 | Phosphorylation | Uniprot | |
| S428 | Phosphorylation | Uniprot | |
| K433 | Ubiquitination | Uniprot | |
| K438 | Acetylation | Uniprot | |
| S477 | Phosphorylation | Uniprot | |
| T523 | Phosphorylation | Uniprot | |
| S526 | Phosphorylation | Uniprot | |
| S558 | Phosphorylation | Uniprot | |
| S559 | Phosphorylation | Uniprot | |
| S562 | Phosphorylation | Uniprot | |
| S563 | Phosphorylation | Uniprot | |
| T567 | Phosphorylation | Uniprot | |
| S573 | Phosphorylation | Uniprot | |
| S662 | Phosphorylation | Uniprot | |
| S678 | Phosphorylation | Uniprot | |
| S699 | Phosphorylation | Uniprot | |
| S705 | Phosphorylation | Uniprot | |
| S724 | Phosphorylation | Uniprot | |
| T738 | Phosphorylation | Uniprot | |
| K751 | Ubiquitination | Uniprot | |
| K904 | Ubiquitination | Uniprot | |
| T920 | Phosphorylation | Uniprot | |
| T924 | Phosphorylation | Uniprot | |
| K952 | Ubiquitination | Uniprot | |
| K972 | Ubiquitination | Uniprot | |
| K982 | Ubiquitination | Uniprot | |
| S1012 | Phosphorylation | Uniprot | |
| T1020 | Phosphorylation | Uniprot | |
| S1032 | Phosphorylation | Uniprot | |
| K1050 | Ubiquitination | Uniprot | |
| S1069 | Phosphorylation | Uniprot | |
| K1071 | Methylation | Uniprot | |
| K1071 | Ubiquitination | Uniprot | |
| S1129 | Phosphorylation | Uniprot | |
| S1132 | Phosphorylation | Uniprot | |
| K1139 | Acetylation | Uniprot | |
| T1145 | Phosphorylation | Uniprot | |
| S1147 | Phosphorylation | Uniprot | |
| S1148 | Phosphorylation | Uniprot | |
| S1149 | Phosphorylation | Uniprot | |
| S1151 | Phosphorylation | Uniprot |
研究背景
Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.
Nucleus.
Interacts with PCNA.
Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
研究领域
· Genetic Information Processing > Replication and repair > Nucleotide excision repair.
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