产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3144, RRID:AB_2835521.
展开/折叠
FE; General transcription factor IIE subunit 2; General transcription factor IIE, polypeptide 2, beta 34kDa; gtf2e2; T2EB_HUMAN; TF2E 2; TF2E2; TFIIE B; TFIIE-beta; Transcription initiation factor IIE beta subunit; Transcription initiation factor IIE subunit beta;
抗原和靶标
- P29084 T2EB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDPSLLRERELFKKRALSTPVVEKRSASSESSSSSSKKKKTKVEHGGSSGSKQNSDHSNGSFNLKALSGSSGYKFGVLAKIVNYMKTRHQRGDTHPLTLDEILDETQHLDIGLKQKQWLMTEALVNNPKIEVIDGKYAFKPKYNVRDKKALLRLLDQHDQRGLGGILLEDIEEALPNSQKAVKALGDQILFVNRPDKKKILFFNDKSCQFSVDEEFQKLWRSVTVDSMDEEKIEEYLKRQGISSMQESGPKKVAPIQRRKKPASQKKRRFKTHNEHLAGVLKDYSDITSSK
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P29084 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| S4 | Phosphorylation | Uniprot | |
| S18 | Phosphorylation | Uniprot | |
| T19 | Phosphorylation | Uniprot | |
| K24 | Acetylation | Uniprot | |
| S26 | Phosphorylation | Uniprot | |
| S29 | Phosphorylation | Uniprot | |
| S35 | Phosphorylation | Uniprot | |
| S36 | Phosphorylation | Uniprot | |
| K52 | Acetylation | Uniprot | |
| S58 | Phosphorylation | Uniprot | |
| S61 | Phosphorylation | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| T87 | Phosphorylation | Uniprot | |
| K114 | Ubiquitination | Uniprot | |
| K116 | Acetylation | Uniprot | |
| T121 | Phosphorylation | Uniprot | |
| K129 | Acetylation | Uniprot | |
| K180 | Ubiquitination | Uniprot | |
| K183 | Ubiquitination | Uniprot | |
| K198 | Acetylation | Uniprot | |
| K206 | Acetylation | Uniprot | |
| K218 | Ubiquitination | Uniprot | |
| S227 | Phosphorylation | Uniprot | |
| K238 | Methylation | Uniprot | |
| K238 | Ubiquitination | Uniprot | |
| S264 | Phosphorylation | Uniprot | |
| K271 | Ubiquitination | Uniprot | |
| K282 | Ubiquitination | Uniprot | |
| Y284 | Phosphorylation | Uniprot |
研究背景
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Nucleus.
Tetramer of two alpha and two beta chains. Interacts with FACT subunit SUPT16H. Interacts with ATF7IP. Interacts with SND1.
Belongs to the TFIIE beta subunit family.
研究领域
· Genetic Information Processing > Transcription > Basal transcription factors.
· Human Diseases > Infectious diseases: Viral > Epstein-Barr virus infection.
· Human Diseases > Cancers: Overview > Viral carcinogenesis.
限制条款
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