| 产品: | BUD31 抗体 |
| 货号: | DF3175 |
| 描述: | Rabbit polyclonal antibody to BUD31 |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 17 KD; 17kD(Calculated). |
| 蛋白号: | P41223 |
| RRID: | AB_2835551 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3175, RRID:AB_2835551.
展开/折叠
Bud31; BUD31 homolog (S. cerevisiae); BUD31_HUMAN; Cwc14; EDG 2; EDG2; fSAP17; Functional spliceosome associated protein 17; G10; G10 maternal transcript homolog; Maternal G10 transcript; Protein BUD31 homolog; Protein EDG-2; Protein G10 homolog; YCR063W;
抗原和靶标
Detected in epithelial and stromal cells in benign prostate hyperplasia tissue (at protein level).
- P41223 BUD31_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPKVKRSRKAPPDGWELIEPTLDELDQKMREAETEPHEGKRKVESLWPIFRIHHQKTRYIFDLFYKRKAISRELYEYCIKEGYADKNLIAKWKKQGYENLCCLRCIQTRDTNFGTNCICRVPKSKLEVGRIIECTHCGCRGCSG
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P41223 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K9 | Ubiquitination | Uniprot | |
| K28 | Ubiquitination | Uniprot | |
| K40 | Ubiquitination | Uniprot | |
| K42 | Sumoylation | Uniprot | |
| K42 | Ubiquitination | Uniprot | |
| K66 | Ubiquitination | Uniprot | |
| K80 | Ubiquitination | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| K91 | Ubiquitination | Uniprot | |
| K94 | Ubiquitination | Uniprot | |
| Y97 | Phosphorylation | Uniprot | |
| T115 | Phosphorylation | Uniprot | |
| K123 | Ubiquitination | Uniprot | |
| K125 | Acetylation | Uniprot | |
| K125 | Sumoylation | Uniprot | |
| K125 | Ubiquitination | Uniprot | |
| R140 | Methylation | Uniprot |
研究背景
Involved in the pre-mRNA splicing process. May play a role as regulator of AR transcriptional activity; may increase AR transcriptional activity.
Nucleus.
Note: Detected in chromatin at the promoter of AR target genes.
Detected in epithelial and stromal cells in benign prostate hyperplasia tissue (at protein level).
Identified in the spliceosome C complex. May interact with AR.
Contains a short sequence motif (Phe-Xaa-Xaa-Phe-Tyr) that can bind to AR and may modulate AR activity.
Belongs to the BUD31 (G10) family.
研究领域
· Genetic Information Processing > Transcription > Spliceosome.
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