| 产品: | DGKE 抗体 |
| 货号: | DF3203 |
| 描述: | Rabbit polyclonal antibody to DGKE |
| 应用: | WB IF/ICC |
| 反应: | Human, Mouse, Rat |
| 预测: | Pig, Bovine, Horse, Sheep, Dog, Chicken |
| 分子量: | 60 KD; 64kD(Calculated). |
| 蛋白号: | P52429 |
| RRID: | AB_2835583 |
产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3203, RRID:AB_2835583.
展开/折叠
AHUS7; DAG kinase epsilon; DAGK 5; DAGK 6; DAGK5; DAGK6; DGK; DGK epsilon; DGK-epsilon; DGKE; DGKE_HUMAN; Diacylglycerol kinase epsilon 64kDa; Diacylglycerol kinase epsilon; Diglyceride kinase epsilon; NPHS7;
抗原和靶标
Expressed predominantly in testis. Expressed in endothelium, platelets and podocytes (at protein level).
- P52429 DGKE_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEAERRPAPGSPSEGLFADGHLILWTLCSVLLPVFITFWCSLQRSRRQLHRRDIFRKSKHGWRDTDLFSQPTYCCVCAQHILQGAFCDCCGLRVDEGCLRKADKRFQCKEIMLKNDTKVLDAMPHHWIRGNVPLCSYCMVCKQQCGCQPKLCDYRCIWCQKTVHDECMKNSLKNEKCDFGEFKNLIIPPSYLTSINQMRKDKKTDYEVLASKLGKQWTPLIILANSRSGTNMGEGLLGEFRILLNPVQVFDVTKTPPIKALQLCTLLPYYSARVLVCGGDGTVGWVLDAVDDMKIKGQEKYIPQVAVLPLGTGNDLSNTLGWGTGYAGEIPVAQVLRNVMEADGIKLDRWKVQVTNKGYYNLRKPKEFTMNNYFSVGPDALMALNFHAHREKAPSLFSSRILNKAVYLFYGTKDCLVQECKDLNKKVELELDGERVALPSLEGIIVLNIGYWGGGCRLWEGMGDETYPLARHDDGLLEVVGVYGSFHCAQIQVKLANPFRIGQAHTVRLILKCSMMPMQVDGEPWAQGPCTVTITHKTHAMMLYFSGEQTDDDISSTSDQEDIKATE
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - P52429 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K101 | Acetylation | Uniprot | |
| K109 | Ubiquitination | Uniprot | |
| K169 | Ubiquitination | Uniprot | |
| K176 | Ubiquitination | Uniprot | |
| K203 | Ubiquitination | Uniprot | |
| Y206 | Phosphorylation | Uniprot | |
| K212 | Ubiquitination | Uniprot | |
| K215 | Ubiquitination | Uniprot | |
| K254 | Ubiquitination | Uniprot | |
| T265 | Phosphorylation | Uniprot | |
| K351 | Ubiquitination | Uniprot | |
| K357 | Ubiquitination | Uniprot | |
| K392 | Ubiquitination | Uniprot | |
| K404 | Ubiquitination | Uniprot | |
| K413 | Ubiquitination | Uniprot |
研究背景
Highly selective for arachidonate-containing species of diacylglycerol (DAG). May terminate signals transmitted through arachidonoyl-DAG or may contribute to the synthesis of phospholipids with defined fatty acid composition.
Membrane>Multi-pass membrane protein. Membrane. Cytoplasm.
Expressed predominantly in testis. Expressed in endothelium, platelets and podocytes (at protein level).
Belongs to the eukaryotic diacylglycerol kinase family.
研究领域
· Environmental Information Processing > Signal transduction > Phosphatidylinositol signaling system.
· Environmental Information Processing > Signal transduction > Phospholipase D signaling pathway. (View pathway)
· Human Diseases > Cancers: Overview > Choline metabolism in cancer. (View pathway)
· Metabolism > Lipid metabolism > Glycerolipid metabolism.
· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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