产品描述
*The optimal dilutions should be determined by the end user.
*Tips:
WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.
引用格式: Affinity Biosciences Cat# DF3274, RRID:AB_2835642.
展开/折叠
ARF GAP GIT2; ARF GTPase activating protein GIT2; ARF GTPase-activating protein GIT2; CAT 2; CAT-2; CAT2; Cool associated tyrosine phosphorylated protein 2; Cool interacting tyrosine phosphorylated protein 2; Cool-interacting tyrosine-phosphorylated protein 2; DKFZp686G01261; G protein coupled receptor kinase interacting ArfGAP 2; G protein coupled receptor kinase interactor 2; G protein-coupled receptor kinase-interactor 2; GIT 2; GIT2; GIT2_HUMAN; GRK interacting protein 2; GRK-interacting protein 2; KIAA0148; MGC760;
抗原和靶标
- Q14161 GIT2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQGSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKSLDSDLSDGPVTVQEFMEVKNALVASEAKIQQLMKVNNNLSDELRIMQKKLQTLQSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEASRPEESRMRLQPFPAHIGRSALVTSSSSLPSFPSTLSWSRDESARRASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWPGDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN
种属预测
score>80的预测可信度较高，可尝试用于WB检测。*预测模型主要基于免疫原序列比对，结果仅作参考，不作为质保凭据。
High(score>80) Medium(80>score>50) Low(score<50) No confidence
翻译修饰 - Q14161 作为底物
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S7 | Phosphorylation | Uniprot | |
| S8 | Phosphorylation | Uniprot | |
| S36 | Phosphorylation | Uniprot | |
| K98 | Ubiquitination | Uniprot | |
| K103 | Ubiquitination | Uniprot | |
| S127 | Phosphorylation | Uniprot | |
| K131 | Ubiquitination | Uniprot | |
| K135 | Ubiquitination | Uniprot | |
| S154 | Phosphorylation | Uniprot | |
| T195 | Phosphorylation | Q13315 (ATM) | Uniprot |
| Y286 | Phosphorylation | Uniprot | |
| S361 | Phosphorylation | Uniprot | |
| S365 | Phosphorylation | Uniprot | |
| K366 | Ubiquitination | Uniprot | |
| T375 | Phosphorylation | Uniprot | |
| S381 | Phosphorylation | Uniprot | |
| S384 | Phosphorylation | Q13315 (ATM) | Uniprot |
| Y392 | Phosphorylation | Uniprot | |
| S394 | Phosphorylation | Uniprot | |
| S397 | Phosphorylation | Uniprot | |
| T401 | Phosphorylation | Uniprot | |
| T405 | Phosphorylation | Uniprot | |
| T406 | Phosphorylation | Uniprot | |
| S408 | Phosphorylation | Uniprot | |
| S415 | Phosphorylation | Uniprot | |
| S418 | Phosphorylation | Uniprot | |
| S421 | Phosphorylation | Uniprot | |
| T426 | Phosphorylation | Uniprot | |
| K434 | Ubiquitination | Uniprot | |
| K443 | Ubiquitination | Uniprot | |
| K449 | Ubiquitination | Uniprot | |
| K464 | Ubiquitination | Uniprot | |
| K477 | Ubiquitination | Uniprot | |
| T480 | Phosphorylation | Uniprot | |
| T481 | Phosphorylation | Uniprot | |
| Y484 | Phosphorylation | Uniprot | |
| T488 | Phosphorylation | Uniprot | |
| S490 | Phosphorylation | Uniprot | |
| Y492 | Phosphorylation | Uniprot | |
| T493 | Phosphorylation | Uniprot | |
| T495 | Phosphorylation | Uniprot | |
| S496 | Phosphorylation | Uniprot | |
| S500 | Phosphorylation | Uniprot | |
| S506 | Phosphorylation | Uniprot | |
| S510 | Phosphorylation | Uniprot | |
| S514 | Phosphorylation | Uniprot | |
| Y516 | Phosphorylation | Uniprot | |
| T518 | Phosphorylation | Uniprot | |
| S520 | Phosphorylation | Uniprot | |
| Y525 | Phosphorylation | Uniprot | |
| S532 | Phosphorylation | Uniprot | |
| S557 | Phosphorylation | Uniprot | |
| S558 | Phosphorylation | Uniprot | |
| S559 | Phosphorylation | Uniprot | |
| S562 | Phosphorylation | Uniprot | |
| S565 | Phosphorylation | Uniprot | |
| S568 | Phosphorylation | Uniprot | |
| S570 | Phosphorylation | Uniprot | |
| S586 | Phosphorylation | Uniprot | |
| T587 | Phosphorylation | Uniprot | |
| S590 | Phosphorylation | Uniprot | |
| Y592 | Phosphorylation | Uniprot | |
| S614 | Phosphorylation | Uniprot | |
| S668 | Phosphorylation | Uniprot | |
| S673 | Phosphorylation | Uniprot | |
| S693 | Phosphorylation | Uniprot | |
| T698 | Phosphorylation | Uniprot | |
| S699 | Phosphorylation | Uniprot | |
| S724 | Phosphorylation | Uniprot | |
| K747 | Ubiquitination | Uniprot |
研究背景
GTPase-activating protein for the ADP ribosylation factor family.
Interacts with TGFB1I1 (By similarity). Interacts with G protein-coupled receptor kinases. Associates with paxillin. Also interacts with PIX exchange factors. Identified in a complex with ARHGEF6 and BIN2.
研究领域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
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