产品: ZNF436 抗体
货号: DF3424
描述: Rabbit polyclonal antibody to ZNF436
应用: WB IF/ICC
反应: Human
预测: Pig, Bovine, Horse, Sheep, Dog
分子量: 50 KD; 54kD(Calculated).
蛋白号: Q9C0F3
RRID: AB_2835724

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产品描述

来源:
Rabbit
应用:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: 适用于变性蛋白样本的免疫印迹检测. IHC: 适用于组织样本的石蜡(IHC-p)或冰冻(IHC-f)切片样本的免疫组化/荧光检测. IF/ICC: 适用于细胞样本的荧光检测. ELISA(peptide): 适用于抗原肽的ELISA检测.

反应:
Human
预测:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Dog(100%)
克隆:
Polyclonal
特异性:
ZNF436 Antibody detects endogenous levels of total ZNF436.
RRID:
AB_2835724
引用格式: Affinity Biosciences Cat# DF3424, RRID:AB_2835724.
偶联:
Unconjugated.
纯化:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
别名:

展开/折叠

HGNC:20814; KIAA1710; Zfp46; Zinc finger protein 436; ZN436_HUMAN; ZNF; ZNF436;

抗原和靶标

免疫原:
Uniprot:
基因/基因ID:
表达:
Q9C0F3 ZN436_HUMAN:

Expressed in fetal brain, heart, liver, spleen, bladder, lung, skin, skeletal muscle, stomach and pancreas.

序列:
MAATLLMAGSQAPVTFEDMAMYLTREEWRPLDAAQRDLYRDVMQENYGNVVSLDFEIRSENEVNPKQEISEDVQFGTTSERPAENAEENPESEEGFESGDRSERQWGDLTAEEWVSYPLQPVTDLLVHKEVHTGIRYHICSHCGKAFSQISDLNRHQKTHTGDRPYKCYECGKGFSRSSHLIQHQRTHTGERPYDCNECGKSFGRSSHLIQHQTIHTGEKPHKCNECGKSFCRLSHLIQHQRTHSGEKPYECEECGKSFSRSSHLAQHQRTHTGEKPYECNECGRGFSERSDLIKHYRVHTGERPYKCDECGKNFSQNSDLVRHRRAHTGEKPYHCNECGENFSRISHLVQHQRTHTGEKPYECNACGKSFSRSSHLITHQKIHTGEKPYECNECWRSFGERSDLIKHQRTHTGEKPYECVQCGKGFTQSSNLITHQRVHTGEKPYECTECEKSFSRSSALIKHKRVHTD

种属预测

种属预测:

score>80的预测可信度较高,可尝试用于WB检测。*预测模型主要基于免疫原序列比对,结果仅作参考,不作为质保凭据。

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

翻译修饰 - Q9C0F3 作为底物

Site PTM Type Enzyme
S10 Phosphorylation
K167 Sumoylation
T271 Phosphorylation
T273 Phosphorylation
T301 Phosphorylation
T355 Phosphorylation
T357 Phosphorylation
T385 Phosphorylation
T411 Phosphorylation
T413 Phosphorylation
Y418 Phosphorylation
K425 Sumoylation
T441 Phosphorylation
S456 Phosphorylation
K465 Methylation

研究背景

功能:

May be a transcriptional repressor.

细胞定位:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
组织特异性:

Expressed in fetal brain, heart, liver, spleen, bladder, lung, skin, skeletal muscle, stomach and pancreas.

蛋白家族:

Belongs to the krueppel C2H2-type zinc-finger protein family.

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